BeiGene (ONC) had the highest return in Q3 2017 by a large-cap US stock, returning 128.8%.

ASSET	QUARTER	% RETURN
BeiGene (ONC)	Q3 2017	128.84%
Insmed (INSM)	Q3 2017	80.2%
Sociedad Quimica y Minera de Chile SA ADR B (SQM)	Q3 2017	69.76%
Roku (ROKU)	Q3 2017	68.19%
Centrais Electricas Brasileiras (EBR)	Q3 2017	63.16%
Stellantis (STLA)	Q3 2017	62.97%
NRG Energy (NRG)	Q3 2017	47.76%
Huazhu (HTHT)	Q3 2017	47.16%
Alnylam Pharmaceuticals (ALNY)	Q3 2017	45.17%
Centrais Elétricas Brasileiras SA - Eletrobrás (EBR.B)	Q3 2017	43.03%
Suzano Papel e Celulose SA ADR (SUZ)	Q3 2017	39.31%
Take-Two Interactive Software (TTWO)	Q3 2017	39.03%
Texas Pacific Land Trust (TPL)	Q3 2017	38.23%
Baidu (BIDU)	Q3 2017	37.68%
Cenovus Energy (CVE)	Q3 2017	36.76%
STMicroelectronics NV ADR (STM)	Q3 2017	34.2%
Sarepta Therapeutics (SRPT)	Q3 2017	34.16%
Shopify (SHOP)	Q3 2017	33.67%
Banco Bradesco S/A ADR (BBDO)	Q3 2017	33.53%
Ovintiv (OVV)	Q3 2017	33.15%
Neurocrine Biosciences (NBIX)	Q3 2017	33.13%
EXACT Sciences (EXAS)	Q3 2017	32.92%
Micron Technology (MU)	Q3 2017	30.71%
ASML Holding NV ADR (ASML)	Q3 2017	30.59%
ON Semiconductor (ON)	Q3 2017	30.44%

Large-cap stocks are treated as having a market cap of $10B+.