Soleno Therapeutics (SLNO) had the highest return in September 2023 by a US stock with a market cap of $2B+, returning 495%.

ASSET	MONTH	% RETURN
Soleno Therapeutics (SLNO)	September 2023	494.96%
Crinetics Pharmaceuticals (CRNX)	September 2023	69.94%
Immunovant (IMVT)	September 2023	67.42%
Biohaven Pharmaceutical (BHVN)	September 2023	41.21%
SharkNinja (SN)	September 2023	32.76%
Wave Life Sciences (WVE)	September 2023	31.58%
Arch Resources (ARCH)	September 2023	28.32%
Warrior Met Coal (HCC)	September 2023	27%
Alpha Metallurgical Resources (AMR)	September 2023	26.12%
TAL Education (TAL)	September 2023	24.62%
CCC Intelligent Solutions Holdings Inc Common Stock (CCCS)	September 2023	24.3%
Consol Energy (CEIX)	September 2023	19.66%
Nextnav Acquisition (NN)	September 2023	18.98%
Peabody Energy (BTU)	September 2023	18.14%
VEON (VEON)	September 2023	17.97%
Alignment Healthcare LLC (ALHC)	September 2023	17.83%
Uranium Energy (UEC)	September 2023	17.58%
Sea (SE)	September 2023	16.61%
Mobileye Global Inc Class A Common Stock (MBLY)	September 2023	16.32%
Summit Therapeutics (SMMT)	September 2023	15.43%
Insmed (INSM)	September 2023	14.56%
Liberty Oilfield Services (LBRT)	September 2023	14.22%
AeroVironment (AVAV)	September 2023	14.09%
Scholar Rock (SRRK)	September 2023	13.42%
Alliance Resource Partners (ARLP)	September 2023	12.42%