Tectonic Therapeutic (TECX) has had the highest return between 2020 and 2024 by a US stock, returning 4,319,900%.

ASSET	YEARS	% RETURN
Tectonic Therapeutic (TECX)	2020-2024	4,319,900%
Gorilla Technology (GRRR)	2020-2024	1,111,900%
Cadrenal Therapeutics, Inc Common Stock (CVKD)	2020-2024	863,900%
MGO Global Inc Common Stock (MGOL)	2020-2024	317,900%
AppTech Payments Corp Warrant (APCXW)	2020-2024	158,900%
Asset Entities Inc Class B Common Stock (ASST)	2020-2024	139,900%
Jianzhi Education Technology Group Company Limited American Depositary Shares (JZ)	2020-2024	109,937.5%
authID (AUID)	2020-2024	91,306.25%
Zhihu Inc ADR (ZH)	2020-2024	50,310.96%
Digihost Technology (DGHI)	2020-2024	27,614.29%
Applied Digital (APLD)	2020-2024	20,166.2%
Ainos (AIMD)	2020-2024	11,275%
XORTX Therapeutics (XRTX)	2020-2024	9,639.13%
Azitra (AZTR)	2020-2024	6,767.86%
Agape ATP Corporation Common Stock (ATPC)	2020-2024	6,357.14%
Digital Brands (DBGIW)	2020-2024	5,061.29%
Kaival Brands Innovations (KAVL)	2020-2024	4,082.5%
ZyVersa Therapeutics (ZVSA)	2020-2024	3,814.59%
CPI Card (PMTS)	2020-2024	3,518.89%
Bone Biologics Corp Warrants (BBLGW)	2020-2024	3,162.91%
Innodata (INOD)	2020-2024	2,899.12%
Perpetua Resources (PPTA)	2020-2024	2,388.27%
Marathon Digital (MARA)	2020-2024	2,355.68%
MicroStrategy (MSTR)	2020-2024	2,347.77%
Alpha Metallurgical Resources (AMR)	2020-2024	2,335.43%