Vista Oil Gas ADR (VIST) had the highest return between 2021 and 2024 by a mid-cap US stock, returning 1,989.2%.

ASSET	YEARS	% RETURN
Vista Oil Gas ADR (VIST)	2021-2024	1,989.19%
Alpha Metallurgical Resources (AMR)	2021-2024	1,757.33%
Consol Energy (CEIX)	2021-2024	1,491.98%
Weatherford International (WFRD)	2021-2024	1,113.43%
Tecnoglass (TGLS)	2021-2024	1,084.23%
Empresa Distribuidora y Comercializadora Norte SA ADR (EDN)	2021-2024	914.42%
Modine Manufacturing (MOD)	2021-2024	818.62%
Sterling Construction (STRL)	2021-2024	801.77%
Peabody Energy (BTU)	2021-2024	770.65%
ADMA Biologics (ADMA)	2021-2024	749.01%
Alliance Resource Partners (ARLP)	2021-2024	739.21%
Dillards (DDS)	2021-2024	731.82%
Powell Industries (POWL)	2021-2024	721.27%
Banco Macro SA B ADR (BMA)	2021-2024	700.58%
BBVA Banco Frances SA ADR (BBAR)	2021-2024	698.76%
Abercrombie & Fitch (ANF)	2021-2024	628.77%
Viking Therapeutics (VKTX)	2021-2024	605.96%
Lantheus (LNTH)	2021-2024	562.18%
Verona Pharma PLC ADR (VRNA)	2021-2024	558.72%
SM Energy (SM)	2021-2024	553.42%
Pampa Energia SA ADR (PAM)	2021-2024	539.56%
Catalyst Pharmaceuticals (CPRX)	2021-2024	526.73%
Biohaven Pharmaceutical (BHVN)	2021-2024	522.5%
Tidewater (TDW)	2021-2024	522.41%
Globalstar (GSAT)	2021-2024	521.81%

Mid-cap stocks are treated as having a market cap between $2B and $10B.