Summit Therapeutics (SMMT) has had the highest return this month by a large-cap US stock, returning 28.2%.

ASSET	MONTH	% RETURN
Summit Therapeutics (SMMT)	April 2025	28.24%
Korea Electric Power Corp ADR (KEP)	April 2025	19.33%
Harmony Gold Mining (HMY)	April 2025	18.66%
GameStop (GME)	April 2025	17.69%
Kinross Gold (KGC)	April 2025	17%
Newmont Goldcorp (NEM)	April 2025	13.87%
AngloGold Ashanti (AU)	April 2025	13.82%
America Movil SAB de CV ADR (AMX)	April 2025	13.75%
Royal Gold (RGLD)	April 2025	13.73%
Palantir Technologies Inc Class A Common Stock (PLTR)	April 2025	11.79%
HDFC Bank Limited ADR (HDB)	April 2025	11.28%
Agnico Eagle Mines (AEM)	April 2025	11.08%
Alamos Gold (AGI)	April 2025	10.7%
Pilgrims Pride (PPC)	April 2025	10.43%
National Grid PLC ADR (NGG)	April 2025	10.41%
Bentley Systems (BSY)	April 2025	9.73%
Ross Stores (ROST)	April 2025	9.19%
Align Technology (ALGN)	April 2025	9.14%
Chewy (CHWY)	April 2025	9%
Murphy USA (MUSA)	April 2025	8.95%
Booz Allen Hamilton (BAH)	April 2025	8.8%
Franco-Nevada (FNV)	April 2025	8.66%
Comfort Systems USA (FIX)	April 2025	8.58%
Maplebear (CART)	April 2025	8.34%
Wheaton Precious Metals (WPM)	April 2025	8.22%

Large-cap stocks are treated as having a market cap of $10B+.