Centene (CNC) had the best month in October 2006 by a large-cap US stock in October 2006, returning 43.8%.

ASSET	MONTH	% RETURN
Centene (CNC)	October 2006	43.84%
Alnylam Pharmaceuticals (ALNY)	October 2006	34.61%
Illumina (ILMN)	October 2006	34.11%
United Airlines (UAL)	October 2006	33.26%
Regeneron Pharmaceuticals (REGN)	October 2006	28.77%
Skyworks Solutions (SWKS)	October 2006	27.5%
Evercore Partners (EVR)	October 2006	27.36%
Pentair (PNR)	October 2006	25.98%
F5 Networks (FFIV)	October 2006	24.96%
U-Haul (UHAL)	October 2006	24.22%
ArcelorMittal SA ADR (MT)	October 2006	23.34%
Manhattan Associates (MANH)	October 2006	22.99%
Align Technology (ALGN)	October 2006	22.65%
Axon Enterprise (AXON)	October 2006	22.5%
CBRE Group Inc Class A (CBRE)	October 2006	22.07%
Logitech International (LOGI)	October 2006	22%
Netflix (NFLX)	October 2006	21.37%
Vertex Pharmaceuticals (VRTX)	October 2006	21.19%
Chipotle Mexican Grill (CMG)	October 2006	20.6%
Albemarle (ALB)	October 2006	20.31%
Norfolk Southern (NSC)	October 2006	19.78%
Steel Dynamics (STLD)	October 2006	19.5%
Amazon (AMZN)	October 2006	19.11%
Alphabet Inc Class A (GOOGL)	October 2006	18.53%
NVIDIA (NVDA)	October 2006	18.39%

Large-cap stocks are treated as having a market cap of $10B+.