NetEase (NTES) had the highest return between 2002 and 2009 by a large-cap US stock, returning 19,967.8%.

ASSET	YEARS	% RETURN
NetEase (NTES)	2002-2009	19,967.79%
Monster Beverage (MNST)	2002-2009	7,139.82%
Bancolombia SA ADR (CIB)	2002-2009	3,898.25%
Banco Bradesco SA ADR (BBD)	2002-2009	3,796.98%
ArcelorMittal SA ADR (MT)	2002-2009	3,090.45%
Southern Copper (SCCO)	2002-2009	2,672.91%
Vale SA ADR (VALE)	2002-2009	2,310.47%
Deckers Outdoor (DECK)	2002-2009	2,200.94%
Apple (AAPL)	2002-2009	1,811.3%
Clean Harbors (CLH)	2002-2009	1,679.4%
Tenaris SA ADR (TS)	2002-2009	1,470.66%
Intuitive Surgical (ISRG)	2002-2009	1,448.03%
Alamos Gold (AGI)	2002-2009	1,434.57%
Cognizant Technology Solutions Corp Class A (CTSH)	2002-2009	1,229.47%
Petroleo Brasileiro Petrobras SA ADR (PBR)	2002-2009	1,226.47%
Petróleo Brasileiro SA - Petrobras (PBR.A)	2002-2009	1,209.41%
Canadian Natural Resources (CNQ)	2002-2009	1,183.37%
Amazon (AMZN)	2002-2009	1,130.07%
Trip Group Ltd ADR (TCOM)	2002-2009	1,118.93%
Ambev SA ADR (ABEV)	2002-2009	1,103.18%
BHP (BHP)	2002-2009	1,076.51%
Credicorp (BAP)	2002-2009	1,017.2%
Itau Unibanco Banco (ITUB)	2002-2009	973.85%
Telkom Indonesia (Persero) Tbk PT ADR Rep 100 B (TLK)	2002-2009	907.16%
United Therapeutics (UTHR)	2002-2009	902.86%

Large-cap stocks are treated as having a market cap of $10B+.