The Philadelphia Phillies have lost the most games by a team, with 11,339 losses.

Interpreted as:

worst team regular-season loss in MLB history

	TEAM	L	W	L%	G	W%	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Phillies	11,339	10,222	.526	21,676	.474	741,678	96,237	193,123	33,384	6,676	14,164	86,465	67,687	5,407	105,198	14,945	2,911	829,695	282,351	54,224	11,914	3,009	3,738	9,852	.260	.326	.381	.706
2	Braves	10,964	11,126	.496	22,244	.504	761,589	99,429	197,805	32,080	6,296	15,040	86,479	67,439	5,060	99,984	14,082	3,061	849,642	287,597	53,416	12,681	2,873	3,651	10,373	.260	.323	.378	.701
3	Pirates	10,837	10,850	.500	21,827	.500	747,684	97,118	196,820	32,330	8,932	12,242	86,628	64,255	5,523	99,441	15,668	3,265	833,255	283,740	53,504	12,557	3,113	3,696	10,037	.263	.325	.379	.704
4	Reds	10,779	10,949	.496	21,867	.504	745,097	98,140	194,151	32,348	7,555	14,304	87,287	66,643	5,500	102,091	18,144	3,401	833,102	284,521	54,207	12,661	3,033	3,645	9,706	.261	.325	.382	.707
5	Cubs	10,779	11,344	.487	22,284	.513	762,592	102,592	199,724	33,723	7,355	15,222	88,182	68,507	5,281	104,915	15,776	3,066	852,308	293,823	56,300	13,026	2,902	3,518	9,950	.262	.326	.385	.711
6	Orioles	10,101	9,130	.525	19,341	.475	656,972	83,524	169,532	29,294	4,909	14,412	77,221	63,234	4,470	98,166	10,537	2,777	738,303	251,880	48,615	10,530	3,097	2,574	10,827	.258	.326	.383	.709
7	Dodgers	10,078	11,450	.468	21,667	.532	738,237	97,777	192,859	31,017	7,000	14,100	88,003	68,820	5,144	100,186	17,322	3,547	828,101	280,176	52,117	12,771	3,053	3,729	9,925	.261	.327	.380	.707
8	Giants	10,029	11,560	.465	21,752	.535	742,393	100,586	195,286	31,323	7,035	15,566	90,061	68,245	5,668	99,419	16,511	3,140	830,977	287,377	53,924	11,662	3,009	4,016	10,168	.263	.329	.387	.716
9	Cardinals	9,986	10,517	.487	20,634	.513	705,831	92,314	187,579	31,796	7,049	12,839	84,381	64,128	5,187	98,009	15,006	3,610	790,251	271,990	51,684	11,971	3,134	3,775	10,121	.266	.330	.385	.715
10	Twins	9,971	9,271	.518	19,351	.482	660,122	85,084	173,121	29,729	6,331	11,992	78,329	62,311	5,152	94,312	12,005	3,074	740,936	251,488	48,052	10,189	3,162	2,661	10,959	.262	.329	.381	.710
11	Athletics	9,873	9,343	.514	19,303	.486	654,274	85,202	168,412	29,165	5,331	14,119	78,507	64,448	4,725	98,859	12,093	3,205	737,225	250,596	48,615	10,680	3,098	2,267	10,599	.257	.327	.383	.710
12	White Sox	9,633	9,601	.501	19,337	.499	654,768	84,006	170,028	28,179	5,550	12,271	77,216	62,036	5,243	91,906	13,607	3,481	737,630	246,120	46,000	12,365	3,218	2,461	10,507	.260	.327	.376	.703
13	Tigers	9,577	9,694	.497	19,364	.503	660,322	88,899	174,456	29,555	6,294	14,547	81,860	65,494	4,436	96,552	11,283	2,935	744,363	260,240	50,396	11,009	3,102	2,446	10,699	.264	.333	.394	.727
14	Guardians	9,381	9,867	.487	19,339	.513	659,168	87,440	174,526	31,119	5,496	13,897	80,810	62,559	4,828	94,443	11,894	3,383	741,367	258,328	50,512	11,460	3,352	2,542	10,516	.265	.331	.392	.723
15	Red Sox	9,277	9,971	.482	19,331	.518	661,596	90,280	176,544	33,090	5,596	14,576	83,718	66,763	4,795	95,402	9,619	2,545	747,083	264,554	53,262	10,592	3,337	2,995	11,539	.267	.337	.400	.737
16	Yankees	8,159	10,795	.430	19,042	.570	648,991	92,522	172,304	28,600	5,491	17,286	85,967	68,513	4,919	94,685	11,639	2,799	735,293	263,744	51,377	9,594	3,276	2,826	10,672	.265	.339	.406	.745
17	Rangers	5,315	4,833	.524	10,154	.476	346,650	45,696	89,428	15,946	1,890	10,177	43,175	32,825	2,691	65,018	5,927	2,843	387,954	139,685	28,013	2,962	2,826	2,250	7,787	.258	.325	.403	.727
18	Mets	5,157	4,835	.516	10,000	.484	338,332	41,244	84,531	15,103	1,813	8,551	38,832	32,327	2,846	64,797	5,868	2,733	380,103	128,913	25,467	3,986	2,612	3,136	7,439	.250	.318	.381	.699
19	Angels	5,130	5,033	.505	10,166	.495	344,930	43,984	88,264	15,256	1,808	9,188	41,387	32,258	2,816	62,545	6,038	3,096	386,306	134,700	26,252	3,535	2,767	2,482	7,864	.256	.322	.391	.713
20	Astros	4,978	5,023	.498	10,006	.502	339,571	42,665	86,551	15,873	2,169	8,402	40,150	32,289	2,891	62,777	7,145	3,129	381,489	131,968	26,444	4,027	2,711	3,144	7,389	.255	.322	.389	.711
21	Padres	4,728	4,144	.533	8,874	.467	299,979	35,952	74,802	13,239	1,756	7,242	33,810	28,560	2,119	59,333	5,994	2,600	336,607	113,279	22,237	3,708	2,241	2,685	6,490	.249	.317	.378	.694
22	Royals	4,638	4,222	.523	8,862	.477	303,110	38,764	79,593	14,880	2,284	6,985	36,582	25,955	2,454	52,003	7,070	2,892	336,547	119,996	24,149	2,364	2,664	1,865	6,768	.263	.323	.396	.719
23	Nationals	4,584	4,278	.517	8,866	.483	299,859	37,138	76,091	14,674	1,787	7,584	34,904	28,197	2,611	57,012	6,527	2,770	336,824	117,091	24,045	3,876	2,281	2,880	6,488	.254	.321	.390	.712
24	Brewers	4,545	4,322	.513	8,871	.487	301,154	39,451	77,137	14,377	1,755	8,691	37,375	28,974	2,703	58,754	5,959	2,725	338,403	121,097	24,823	3,160	2,412	2,155	6,600	.256	.325	.402	.727
25	Mariners	3,962	3,615	.523	7,579	.477	258,530	33,656	66,440	12,392	1,258	7,707	31,970	24,512	2,345	49,569	5,011	2,167	289,402	104,469	21,357	1,944	2,071	1,664	5,664	.257	.325	.404	.729