The Houston Astros scored the most runs by a team in 2021, with 863 runs.

	TEAM	R	SEASON	G	W%	W	L	AB	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Astros	863	2021	162	.586	95	67	5,593	1,496	299	14	221	834	569	64	1,222	53	16	6,289	2,486	534	9	54	25	136	.267	.339	.444	.783
2	Rays	857	2021	162	.617	100	62	5,507	1,336	288	36	222	810	585	72	1,542	88	42	6,211	2,362	546	6	41	27	75	.243	.321	.429	.750
3	Blue Jays	846	2021	162	.562	91	71	5,476	1,455	285	13	262	816	496	51	1,218	81	20	6,068	2,552	560	10	35	14	112	.266	.330	.466	.797
4	Dodgers	830	2021	162	.654	106	56	5,445	1,330	247	24	237	799	613	104	1,408	65	17	6,239	2,336	508	32	45	36	96	.244	.330	.429	.759
5	Red Sox	829	2021	162	.568	92	70	5,495	1,434	330	23	219	783	512	61	1,386	40	21	6,120	2,467	572	10	42	22	100	.261	.328	.449	.777
6	Giants	804	2021	162	.660	107	55	5,462	1,360	271	25	241	768	602	64	1,461	66	14	6,194	2,404	537	36	30	45	117	.249	.329	.440	.769
7	White Sox	796	2021	162	.574	93	69	5,357	1,373	275	22	190	757	586	78	1,389	57	20	6,084	2,262	487	24	39	10	139	.256	.336	.422	.758
8	Braves	790	2021	161	.547	88	73	5,363	1,307	269	20	239	762	549	67	1,453	59	19	6,054	2,333	528	32	43	36	81	.244	.319	.435	.754
9	Reds	786	2021	162	.512	83	79	5,423	1,352	295	13	222	756	553	105	1,425	36	24	6,161	2,339	530	35	45	22	129	.249	.328	.431	.759
10	Athletics	743	2021	162	.531	86	76	5,395	1,284	271	19	199	698	545	98	1,349	88	20	6,104	2,190	489	17	49	17	99	.238	.317	.406	.723
11	Rockies	739	2021	161	.460	74	87	5,374	1,338	275	34	182	709	491	58	1,356	76	23	6,007	2,227	491	48	36	24	98	.249	.317	.414	.731
12	Brewers	738	2021	162	.586	95	67	5,362	1,251	255	18	194	700	586	88	1,465	82	21	6,096	2,124	467	25	35	26	102	.233	.317	.396	.713
13	Phillies	734	2021	162	.506	82	80	5,366	1,288	262	24	198	700	564	67	1,402	77	19	6,087	2,192	484	47	43	37	103	.240	.318	.408	.726
14	Twins	729	2021	162	.451	73	89	5,431	1,311	271	17	228	690	525	70	1,405	54	15	6,075	2,300	516	7	42	17	122	.241	.314	.423	.738
15	Padres	729	2021	162	.488	79	83	5,384	1,305	273	21	180	695	586	61	1,324	110	39	6,113	2,160	474	36	46	42	121	.242	.321	.401	.722
16	Nationals	724	2021	162	.401	65	97	5,385	1,388	272	20	182	686	573	84	1,303	56	26	6,111	2,246	474	38	31	43	158	.258	.337	.417	.754
17	Angels	723	2021	162	.475	77	85	5,437	1,331	265	23	190	691	464	59	1,394	79	26	6,015	2,212	478	30	25	35	107	.245	.310	.407	.717
18	Indians	717	2021	162	.494	80	82	5,332	1,269	248	22	203	686	453	64	1,387	109	17	5,905	2,170	473	20	36	18	105	.238	.303	.407	.710
19	Yankees	711	2021	162	.568	92	70	5,331	1,266	213	12	222	666	621	63	1,482	63	18	6,059	2,169	447	10	34	14	154	.237	.322	.407	.729
20	Cardinals	706	2021	162	.556	90	72	5,351	1,303	261	22	198	678	478	86	1,341	89	22	5,999	2,202	481	40	44	32	99	.244	.313	.412	.725
21	Cubs	705	2021	162	.438	71	91	5,306	1,255	225	26	210	672	502	92	1,596	86	37	5,970	2,162	461	40	30	17	133	.237	.312	.407	.719
22	Tigers	697	2021	162	.475	77	85	5,376	1,299	236	37	179	675	490	44	1,514	88	25	5,977	2,146	452	17	50	8	113	.242	.308	.399	.707
23	Mariners	697	2021	162	.556	90	72	5,355	1,209	233	11	199	673	535	72	1,492	64	24	6,007	2,061	443	9	36	8	92	.226	.303	.385	.688
24	Royals	686	2021	162	.457	74	88	5,427	1,349	251	29	163	647	421	55	1,258	124	33	5,986	2,147	443	31	52	8	100	.249	.306	.396	.702
25	Diamondbacks	679	2021	162	.321	52	110	5,489	1,297	308	31	144	644	537	54	1,465	43	16	6,140	2,099	483	32	28	24	99	.236	.309	.382	.692