Barry Bonds has smashed the most home runs in a season, with 73 home runs in 2001.

	NAME	HR	SEASON	TM	G	AB	R	H	2B	3B	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS	WRC	WRAA	WOBA	WRC+	BRAA
1	Barry Bonds B. Bonds	73	2001	SFG	153	476	129	156	32	2	137	177	9	93	13	3	664	411	107	0	2	35	5	.328	.515	.863	1.379	200	117.7	.537	234	116.6
2	Mark McGwire M. McGwire	70	1998	STL	155	509	130	152	21	0	147	162	6	155	1	0	681	383	91	0	4	28	8	.299	.470	.752	1.222	176	91.7	.492	205	90.7
3	Sammy Sosa S. Sosa	66	1998	CHC	159	643	134	198	20	0	158	73	1	171	18	9	722	416	86	0	5	14	20	.308	.377	.647	1.024	146	56.6	.425	159	53.7
4	Mark McGwire M. McGwire	65	1999	STL	153	521	118	145	21	1	147	133	2	141	0	0	661	363	87	0	5	21	12	.278	.424	.697	1.120	150	64.2	.453	169	61.5
5	Sammy Sosa S. Sosa	64	2001	CHC	160	577	146	189	34	5	160	116	6	153	0	2	711	425	103	0	12	37	6	.328	.437	.737	1.174	171	82.7	.465	186	79.8
6	Sammy Sosa S. Sosa	63	1999	CHC	162	625	114	180	24	2	141	78	3	171	7	8	712	397	89	0	6	8	17	.288	.367	.635	1.002	138	45.2	.414	143	41.3
7	Aaron Judge A. Judge	62	2022	NYY	157	570	133	177	28	0	131	111	6	175	16	3	692	391	90	0	5	19	14	.311	.425	.686	1.111	161	81.6	.458	208	84.5
8	Roger Maris R. Maris	61	1961	NYY	161	590	132	159	16	4	141	94	7	67	0	0	698	366	81	0	7	0	16	.269	.372	.620	.993	138	55.9	.424	162	55.1
9	Babe Ruth B. Ruth	60	1927	NYY	151	540	158	192	29	8	165	137	0	89	7	6	691	417	97	14				.356	.486	.772	1.258	195	109.9	.545	212	104.8
10	Giancarlo Stanton G. Stanton	59	2017	MIA	159	597	123	168	32	0	132	85	7	163	2	2	692	377	91	0	3	13	13	.281	.376	.631	1.007	137	52.3	.410	158	51.9
11	Babe Ruth B. Ruth	59	1921	NYY	152	540	177	204	44	16	168	145	4	81	17	13	693	457	119	4				.378	.512	.846	1.359	214	127.8	.575	224	118.7
12	Aaron Judge A. Judge	58	2024	NYY	158	559	122	180	36	1	144	133	9	171	10	0	703	392	95	0	2	20	22	.322	.458	.701	1.159	176	93.7	.476	219	95.5
13	Ryan Howard R. Howard	58	2006	PHI	159	581	104	182	25	1	149	108	9	181	0	0	704	383	84	0	6	37	7	.313	.425	.659	1.084	151	63	.436	162	57.5
14	Mark McGwire M. McGwire	58	1997	TOT	156	540	86	148	27	0	123	101	9	159	3	0	657	349	85	0	7	16	9	.274	.393	.646	1.039	134	52.9	.429	161	51.4
15	Hank Greenberg H. Greenberg	58	1938	DET	155	556	143	175	23	4	147	119	3	92	7	5	681	380	85	3				.315	.438	.683	1.122	166	80.3	.489	162	62
16	Jimmie Foxx J. Foxx	58	1932	PHA	154	585	151	213	33	9	169	116	0	96	3	7	701	438	100	0				.364	.469	.749	1.218	193	105.6	.522	198	95.8
17	Alex Rodriguez A. Rodriguez	57	2002	TEX	162	624	125	187	27	2	142	87	10	122	9	4	725	389	86	0	4	12	14	.300	.392	.623	1.015	146	58.9	.424	158	51.5
18	Luis Gonzalez L. Gonzalez	57	2001	ARI	162	609	128	198	36	7	142	100	14	83	1	1	728	419	100	0	5	24	14	.325	.429	.688	1.117	168	77.8	.454	173	69.4
19	Ken Griffey Jr. K. Griffey Jr.	56	1998	SEA	161	633	120	180	33	3	146	76	7	121	20	5	720	387	92	0	4	11	14	.284	.365	.611	.977	135	46	.408	145	41.8
20	Ken Griffey Jr. K. Griffey Jr.	56	1997	SEA	157	608	125	185	34	3	147	76	8	121	15	4	704	393	93	0	12	23	12	.304	.382	.646	1.028	139	52.2	.421	155	49
21	Hack Wilson H. Wilson	56	1930	CHC	155	585	146	208	35	6	191	105	1	84	3		709	423	97	18				.356	.454	.723	1.177	189	89	.497	171	78.9
22	Shohei Ohtani S. Ohtani	54	2024	LAD	159	636	134	197	38	7	130	81	6	162	59	4	728	411	99	0	5	10	7	.310	.390	.646	1.036	156	70.5	.431	181	70.3
23	Matt Olson M. Olson	54	2023	ATL	162	608	127	172	27	3	139	104	4	167	1	0	720	367	84	0	4	8	13	.283	.389	.604	.993	144	56.4	.413	161	54.1
24	Jose Bautista J. Bautista	54	2010	TOR	161	569	109	148	35	3	124	100	10	116	9	2	683	351	92	0	4	2	10	.260	.378	.617	.995	134	55.1	.422	165	52.4
25	Alex Rodriguez A. Rodriguez	54	2007	NYY	158	583	143	183	31	0	156	95	21	120	24	4	708	376	85	0	9	11	15	.314	.422	.645	1.067	155	67.5	.445	175	66.2