Hoyt Wilhelm has struck out the most career batters by a relief pitcher, with 1,363 strikeouts.

	NAME	SO	G	W	L	W%	GS	ERA	CG	SHO	SV	IP	H	ER	R	HR	BB	HBP	GF	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	H/9
1	Hoyt Wilhelm H. Wilhelm	1,363	1,018	124	103	.546	0	2.49	0	0	228	1872.1	1,436	518	636	125	661	51	651	58	7,619	83	6.55	3.18	2.06	0.60	17.9	8.7	1.12	.242	3.06	6.90
2	Rich Gossage R. Gossage	1,340	965	115	85	.575	0	2.77	0	0	310	1556.2	1,235	479	537	98	628	38	681	87	6,408	56	7.75	3.63	2.13	0.57	20.9	9.8	1.20	.264	3.10	7.14
3	Craig Kimbrel C. Kimbrel	1,265	837	56	47	.544	0	2.59	0	0	440	809.2	482	233	259	73	339	40	651	11	3,257	70	14.06	3.77	3.73	0.81	38.8	10.4	1.01	.266	2.88	5.36
4	Aroldis Chapman A. Chapman	1,260	807	57	45	.559	0	2.62	0	0	339	769.1	454	224	248	52	397	33	526	7	3,152	82	14.74	4.64	3.17	0.61	40.0	12.6	1.11	.285	2.90	5.31
5	Kenley Jansen K. Jansen	1,229	880	49	36	.576	0	2.55	0	0	452	876.1	578	248	266	80	265	31	660	18	3,476	21	12.62	2.72	4.64	0.82	35.4	7.6	0.96	.266	2.73	5.94
6	Lee Smith L. Smith	1,225	1,016	71	87	.449	0	2.98	0	0	478	1252.1	1,095	415	456	87	474	9	802	100	5,230	46	8.80	3.41	2.58	0.63	23.4	9.1	1.25	.293	3.28	7.87
7	Billy Wagner B. Wagner	1,196	853	47	40	.540	0	2.31	0	0	422	903.0	601	232	262	82	300	33	703	26	3,600	43	11.92	2.99	3.99	0.82	33.2	8.3	1.00	.261	2.61	5.99
8	Rollie Fingers R. Fingers	1,183	907	107	101	.514	0	2.73	0	0	341	1505.2	1,276	456	502	97	429	29	709	105	6,104	37	7.07	2.56	2.76	0.58	19.4	7.0	1.13	.270	3.00	7.63
9	Jesse Orosco J. Orosco	1,169	1,248	87	78	.527	0	3.12	0	0	144	1277.0	1,035	442	499	112	568	34	501	85	5,374	40	8.24	4.00	2.06	0.79	21.8	10.6	1.26	.264	3.52	7.29
10	Lindy McDaniel L. McDaniel	1,165	913	119	88	.575	0	3.14	0	0	174	1694.2	1,590	591	682	122	486	11	577	120	7,019	92	6.19	2.58	2.40	0.65	16.6	6.9	1.23	.280	3.62	8.44
11	David Robertson D. Robertson	1,153	860	66	46	.589	0	2.91	0	0	177	875.2	656	283	306	77	356	25	354	37	3,609	57	11.85	3.66	3.24	0.79	31.9	9.9	1.16	.290	3.15	6.74
12	Francisco Rodriguez F. Rodriguez	1,142	948	52	53	.495	0	2.86	0	0	437	976.0	738	310	336	98	389	17	677	42	4,011	68	10.53	3.59	2.94	0.90	28.5	9.7	1.15	.271	3.10	6.81
13	Mariano Rivera M. Rivera	1,135	1,105	79	57	.581	0	2.06	0	0	652	1233.2	934	282	305	63	266	44	952	41	4,870	13	8.28	1.94	4.27	0.46	23.3	5.5	0.97	.259	2.23	6.81
14	Trevor Hoffman T. Hoffman	1,133	1,035	61	75	.449	0	2.87	0	0	601	1089.1	846	347	378	100	307	9	856	58	4,388	49	9.36	2.54	3.69	0.83	25.8	7.0	1.06	.263	3.12	6.99
15	Don McMahon D. McMahon	992	872	90	66	.577	0	2.94	0	0	152	1297.0	1,040	424	474	102	576	34	505	82	5,446	74	6.88	4.00	1.72	0.71	18.2	10.6	1.25	.251	3.29	7.22
16	Dan Plesac D. Plesac	990	1,050	62	67	.481	0	3.55	0	0	158	1003.0	907	396	439	98	370	14	422	52	4,229	41	8.88	3.32	2.68	0.88	23.4	8.7	1.27	.293	3.94	8.14
17	Michael Jackson M. Jackson	983	998	61	63	.492	0	3.33	0	0	142	1154.2	948	427	467	119	440	56	422	80	4,810	34	7.66	3.43	2.23	0.93	20.4	9.1	1.20	.258	3.64	7.39
18	John Franco J. Franco	975	1,119	90	87	.508	0	2.89	0	0	424	1245.2	1,166	400	466	81	495	22	774	78	5,312	54	7.04	3.58	1.97	0.59	18.4	9.3	1.33	.290	3.37	8.42
19	Tug McGraw T. McGraw	974	785	89	69	.563	0	2.86	0	0	180	1301.1	1,104	414	467	74	494	20	541	123	5,391	51	6.74	3.42	1.97	0.51	18.1	9.2	1.23	.269	3.23	7.64
20	Octavio Dotel O. Dotel	955	724	50	41	.549	0	3.32	0	0	109	760.0	576	280	306	84	313	31	305	36	3,172	40	11.31	3.71	3.05	0.99	30.1	9.9	1.17	.275	3.62	6.82
21	Armando Benitez A. Benitez	946	762	40	47	.460	0	3.13	0	0	289	779.0	545	271	296	95	403	16	527	32	3,253	18	10.93	4.66	2.35	1.10	29.1	12.4	1.22	.251	3.42	6.30
22	Fernando Rodney F. Rodney	943	951	48	71	.403	0	3.80	0	0	327	933.0	817	394	433	73	464	52	590	38	4,064	65	9.10	4.48	2.03	0.70	23.2	11.4	1.37	.294	4.18	7.88
23	Roberto Hernandez R. Hernandez	940	1,007	66	71	.482	0	3.42	0	0	326	1060.0	992	403	465	95	457	35	667	53	4,583	49	7.98	3.88	2.06	0.81	20.5	10.0	1.37	.294	3.95	8.42
24	Tyler Clippard T. Clippard	921	793	52	46	.531	0	2.99	0	0	74	825.2	576	274	295	101	319	31	212	17	3,365	45	10.04	3.48	2.89	1.10	27.4	9.5	1.08	.238	3.22	6.28
25	Tom Gordon T. Gordon	915	687	65	53	.551	0	3.29	0	0	158	847.1	652	310	329	65	358	16	347	39	3,515	54	9.72	3.80	2.56	0.69	26.0	10.2	1.19	.272	3.49	6.93