Mark Reynolds has the most strikeouts in a season, with 223 strikeouts in 2009.

	NAME	SO	SEASON	TM	G	AB	R	H	2B	3B	HR	RBI	BB	HBP	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS	WRC	WRAA	WOBA	WRC+	BRAA
1	Mark Reynolds M. Reynolds	223	2009	ARI	155	578	98	150	30	1	44	102	76	5	24	9	662	314	75	0	3	3	8	.260	.349	.543	.892	108	28.4	.381	127	22.3
2	Adam Dunn A. Dunn	222	2012	CWS	151	539	87	110	19	0	41	96	105	1	2	1	649	252	60	0	4	3	8	.204	.333	.468	.800	90	16.2	.346	115	11.4
3	Chris Davis C. Davis	219	2016	BAL	157	566	99	125	21	0	38	84	88	8	1	0	665	260	59	0	3	3	6	.221	.332	.459	.792	90	12	.340	113	10.5
4	Elly De La Cruz E. De La Cruz	218	2024	CIN	160	618	105	160	36	10	25	76	69	6	67	16	696	291	71	2	1	2	12	.259	.339	.471	.809	103	21.5	.349	118	14.9
5	Yoán Moncada Y. Moncada	217	2018	CWS	149	578	73	136	32	6	17	61	67	1	12	6	650	231	55	2	2	1	4	.235	.315	.400	.714	74	-1.8	.311	96	-2.8
6	Kyle Schwarber K. Schwarber	215	2023	PHI	160	585	108	115	19	1	47	104	126	6	0	2	720	277	67	0	3	5	4	.197	.343	.474	.817	107	19	.350	120	17.5
7	Eugenio Suárez E. Suárez	214	2023	SEA	162	598	68	139	29	0	22	96	70	15	2	1	694	234	51	0	11	0	10	.232	.323	.391	.714	82	-2.9	.313	104	3.6
8	Joey Gallo J. Gallo	213	2021	TOT	153	498	90	99	13	1	38	77	111	6	6	0	616	228	52	0	1	5	6	.199	.351	.458	.808	92	17.4	.348	121	16.2
9	Chris Carter C. Carter	212	2013	HOU	148	506	64	113	24	2	29	82	70	4	2	0	585	228	55	0	5	1	8	.223	.320	.451	.770	75	10.5	.337	112	8.2
10	Teoscar Hernández T. Hernández	211	2023	SEA	160	625	70	161	29	2	26	93	38	8	7	2	678	272	57	0	7	2	6	.258	.305	.435	.741	82	-1.1	.317	106	5.3
11	Giancarlo Stanton G. Stanton	211	2018	NYY	158	617	102	164	34	1	38	100	70	8	5	0	705	314	73	0	10	5	17	.266	.343	.509	.852	108	25.9	.360	128	24
12	Mark Reynolds M. Reynolds	211	2010	ARI	145	499	79	99	17	2	32	85	83	9	7	4	596	216	51	0	5	7	8	.198	.320	.433	.753	72	4	.329	96	-3.1
13	Aaron Judge A. Judge	208	2017	NYY	155	542	128	154	24	3	52	114	127	5	9	4	678	340	79	0	4	11	15	.284	.422	.627	1.049	145	62.5	.430	174	61.5
14	Chris Davis C. Davis	208	2015	BAL	160	573	100	150	31	0	47	117	84	8	2	3	670	322	78	0	5	6	6	.262	.361	.562	.923	116	40.9	.390	149	38
15	Joey Gallo J. Gallo	207	2018	TEX	148	500	82	103	24	1	40	92	74	3	3	4	577	249	65	0	0	4	3	.206	.312	.498	.810	81	13.4	.343	108	5.7
16	Chris Carter C. Carter	206	2016	MIL	160	549	84	122	27	1	41	94	76	9	3	1	644	274	69	0	10	1	18	.222	.321	.499	.821	91	14.9	.346	113	10.7
17	Drew Stubbs D. Stubbs	205	2011	CIN	158	604	92	147	22	3	15	44	63	7	40	10	681	220	40	6	1	1	2	.243	.321	.364	.686	72	-4.4	.308	91	-7.3
18	Mark Reynolds M. Reynolds	204	2008	ARI	152	539	87	129	28	3	28	97	64	3	11	2	613	247	59	1	6	0	10	.239	.320	.458	.779	79	5	.338	98	-1.9
19	Matt Chapman M. Chapman	202	2021	OAK	151	529	75	111	15	3	27	72	80	4	3	2	622	213	45	0	9	0	6	.210	.314	.403	.716	74	-1.5	.311	102	1.4
20	Ezequiel Tovar E. Tovar	200	2024	COL	157	655	83	176	45	4	26	78	23	4	6	5	694	307	75	5	7	1	16	.269	.295	.469	.763	89	7.9	.324	95	-4.4
21	Kyle Schwarber K. Schwarber	200	2022	PHI	155	577	100	126	21	3	46	94	86	4	10	1	669	291	70	0	2	3	10	.218	.323	.504	.827	100	23.8	.355	129	22.6
22	Kris Bryant K. Bryant	199	2015	CHC	151	559	87	154	31	5	26	99	77	9	13	4	650	273	62	0	5	0	7	.275	.369	.488	.858	103	29.9	.371	136	27.2
23	Chris Davis C. Davis	199	2013	BAL	160	584	103	167	42	1	53	138	72	10	4	1	673	370	96	0	7	12	4	.286	.370	.634	1.004	130	56.3	.421	167	51.4
24	Adam Dunn A. Dunn	199	2010	WSH	158	558	85	145	36	2	38	103	77	9	0	1	648	299	76	0	4	10	10	.260	.356	.536	.892	105	31	.381	136	27.8
25	Ryan Howard R. Howard	199	2008	PHI	162	610	105	153	26	4	48	146	81	3	1	1	700	331	78	0	6	17	11	.251	.339	.543	.881	107	22.6	.368	121	18.2