Gerrit Cole has started the most career games by an active pitcher, with 317 starts.

Interpreted as:

most regular-season starts by an active pitcher

	NAME	GS	G	W	L	W%	ERA	SO	CG	SHO	SV	IP	H	ER	R	HR	BB	HBP	GF	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	ERA-	FIP	FIP-	H/9	PRAA
1	Gerrit Cole G. Cole	317	317	153	80	.657	3.18	2,251	8	5	0	1954.0	1,627	690	740	217	500	61	0	8	7,861	58	10.37	2.30	4.50	1.00	28.6	6.4	1.09	.292	3.41	79	3.16	77	7.49	213.5
2	Sonny Gray S. Gray	298	307	110	94	.539	3.51	1,724	6	4	0	1737.1	1,490	677	743	167	583	54	2	5	7,199	104	8.93	3.02	2.96	0.87	23.9	8.1	1.19	.283	3.85	85	3.52	85	7.72	122.7
3	Chris Sale C. Sale	292	372	138	83	.624	3.04	2,414	16	3	12	1958.1	1,590	661	712	202	455	119	25	15	7,879	45	11.09	2.09	5.31	0.93	30.6	5.8	1.04	.296	3.27	71	2.89	69	7.31	283.7
4	Kevin Gausman K. Gausman	290	329	102	102	.500	3.84	1,765	3	1	0	1718.0	1,680	733	787	212	485	35	11	9	7,211	63	9.25	2.54	3.64	1.11	24.5	6.7	1.26	.311	4.12	92	3.61	85	8.80	116.4
5	Yu Darvish Y. Darvish	282	282	110	88	.556	3.58	2,007	2	1	0	1706.0	1,394	678	712	217	544	77	0	8	7,009	79	10.59	2.87	3.69	1.14	28.6	7.8	1.14	.283	3.76	85	3.53	84	7.35	125.8
6	Kyle Hendricks K. Hendricks	270	276	97	81	.545	3.68	1,259	6	4	0	1580.1	1,501	647	696	184	364	64	4	16	6,518	12	7.17	2.07	3.46	1.05	19.3	5.6	1.18	.283	3.96	90	3.89	95	8.55	40
7	Aaron Nola A. Nola	268	268	104	79	.568	3.70	1,779	6	4	0	1621.1	1,423	667	704	199	421	52	0	16	6,635	17	9.88	2.34	4.23	1.10	26.8	6.3	1.14	.293	3.91	88	3.44	80	7.90	150.7
8	Zack Wheeler Z. Wheeler	259	259	103	70	.595	3.34	1,625	4	3	0	1578.2	1,368	585	635	147	457	68	0	14	6,501	39	9.26	2.61	3.56	0.84	25.0	7.0	1.16	.290	3.62	84	3.31	80	7.80	144.6
9	Michael Wacha M. Wacha	257	278	100	62	.617	3.89	1,290	2	2	0	1454.2	1,405	629	672	179	458	38	4	18	6,130	41	7.98	2.83	2.82	1.11	21.0	7.5	1.28	.294	4.16	96	4.00	98	8.69	7.2
10	Marcus Stroman M. Stroman	252	261	87	85	.506	3.72	1,204	4	2	2	1458.1	1,424	603	672	139	436	39	3	5	6,098	47	7.43	2.69	2.76	0.86	19.7	7.1	1.28	.300	4.15	90	3.73	88	8.79	81.9
11	José Berríos J. Berríos	243	244	99	77	.563	4.07	1,343	5	1	0	1405.2	1,314	636	679	193	417	91	0	5	5,909	34	8.60	2.67	3.22	1.24	22.7	7.1	1.23	.290	4.35	96	4.13	97	8.41	22.9
12	Robbie Ray R. Ray	229	233	77	73	.513	3.98	1,548	1	1	0	1258.2	1,102	557	593	194	535	47	1	19	5,342	53	11.07	3.83	2.89	1.39	29.0	10.0	1.30	.301	4.24	94	4.08	99	7.88	4.5
13	Jon Gray J. Gray	223	228	72	70	.507	4.45	1,211	2	1	0	1216.2	1,191	602	641	155	401	51	3	13	5,172	44	8.96	2.97	3.02	1.15	23.4	7.8	1.31	.309	4.74	97	3.95	90	8.81	57.2
14	Jacob deGrom J. deGrom	218	218	84	57	.596	2.52	1,666	4	2	0	1367.0	1,051	383	420	120	308	22	0	13	5,376	27	10.97	2.03	5.41	0.79	31.0	5.7	0.99	.286	2.77	65	2.58	64	6.92	227.7
15	Luis Castillo L. Castillo	211	211	72	76	.486	3.56	1,331	1	0	0	1230.0	1,040	486	532	151	407	41	0	8	5,079	16	9.74	2.98	3.27	1.10	26.2	8.0	1.18	.282	3.89	85	3.70	87	7.61	75.6
16	Taijuan Walker T. Walker	209	217	72	63	.533	4.19	1,002	3	1	0	1154.1	1,079	538	592	165	392	54	3	13	4,885	26	7.81	3.06	2.56	1.29	20.5	8.0	1.27	.279	4.62	103	4.44	107	8.41	-35
17	Eduardo Rodriguez E. Rodriguez	206	212	85	57	.599	4.08	1,154	0	0	0	1150.1	1,102	521	547	142	395	31	1	7	4,885	13	9.03	3.09	2.92	1.11	23.6	8.1	1.30	.304	4.28	92	3.88	92	8.62	44.8
18	Kyle Freeland K. Freeland	200	205	59	73	.447	4.48	820	0	0	0	1097.2	1,201	546	585	158	354	41	0	10	4,757	15	6.72	2.90	2.32	1.30	17.2	7.4	1.42	.308	4.80	93	4.62	104	9.85	-20.6
19	Jameson Taillon J. Taillon	200	201	71	53	.573	3.89	975	3	1	1	1107.1	1,072	479	516	146	267	32	1	10	4,609	24	7.92	2.17	3.65	1.19	21.2	5.8	1.21	.290	4.19	95	3.92	95	8.71	26.9
20	Sean Manaea S. Manaea	198	228	77	62	.554	4.00	1,109	3	3	0	1184.1	1,088	527	573	158	335	54	3	4	4,933	34	8.43	2.55	3.31	1.20	22.5	6.8	1.20	.284	4.35	98	4.01	97	8.27	16.6
21	Tyler Anderson T. Anderson	197	205	60	64	.484	4.26	941	1	0	0	1122.2	1,082	532	568	156	358	36	1	8	4,747	36	7.54	2.87	2.63	1.25	19.8	7.5	1.28	.284	4.55	97	4.34	102	8.67	-8.4
22	Carlos Rodón C. Rodón	193	198	75	63	.543	3.85	1,206	3	1	0	1086.2	953	465	500	137	404	56	1	5	4,589	61	9.99	3.35	2.99	1.13	26.3	8.8	1.25	.293	4.14	93	3.84	91	7.89	47
23	Chris Bassitt C. Bassitt	187	200	72	56	.563	3.59	1,025	2	2	0	1108.1	1,010	442	479	121	357	83	6	6	4,674	30	8.32	2.90	2.87	0.98	21.9	7.6	1.23	.288	3.89	88	3.93	94	8.20	27.9
24	Miles Mikolas M. Mikolas	182	210	64	64	.500	4.16	795	3	2	0	1096.0	1,108	506	539	138	209	47	10	7	4,549	15	6.53	1.72	3.80	1.13	17.5	4.6	1.20	.289	4.43	102	4.06	100	9.10	0.6
25	Joe Musgrove J. Musgrove	180	206	66	62	.516	3.73	1,050	2	2	2	1056.0	970	438	472	133	262	77	7	10	4,385	21	8.95	2.23	4.01	1.13	23.9	6.0	1.17	.292	4.02	91	3.78	90	8.27	49.3