Nolan Ryan has the most career no-hitters, with 7.

Interpreted as:

most regular-season no hitters by a player in career

	NAME	NH	G	W	L	W%	GS	ERA	SO	CG	SHO	SV	IP	H	ER	R	HR	BB	HBP	GF	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	H/9
1	Nolan Ryan N. Ryan	7	807	324	292	.526	773	3.19	5,714	222	61	3	5386.0	3,923	1,911	2,178	321	2,795	158	13	78	22,575	277	9.55	4.67	2.04	0.54	25.3	12.4	1.25	.265	3.64	6.56
2	Sandy Koufax S. Koufax	4	397	165	87	.655	314	2.76	2,396	137	40	9	2324.1	1,754	713	806	204	817	18	44	48	9,497	87	9.28	3.16	2.93	0.79	25.2	8.6	1.11	.256	3.12	6.79
3	Justin Verlander J. Verlander	3	526	262	147	.641	526	3.30	3,416	26	9	0	3415.2	2,891	1,252	1,354	355	952	115	0	27	13,945	97	9.00	2.51	3.59	0.94	24.5	6.8	1.13	.278	3.57	7.62
4	Bob Feller B. Feller	3	570	266	162	.621	484	3.26	2,581	279	44	22	3827.0	3,271	1,385	1,557	223	1,764	60	52	6	16,172	69	6.07	4.15	1.46	0.52	16.0	10.9	1.32	.264	3.66	7.69
5	Mike Fiers M. Fiers	2	218	75	64	.540	199	4.07	995	2	2	0	1151.0	1,119	521	554	184	340	49	8	7	4,852	60	7.78	2.66	2.93	1.44	20.5	7.0	1.27	.285	4.33	8.75
6	Jake Arrieta J. Arrieta	2	285	115	93	.553	279	3.98	1,433	6	5	0	1612.1	1,450	713	787	181	571	64	1	23	6,755	79	8.00	3.19	2.51	1.01	21.2	8.5	1.25	.282	4.39	8.09
7	Max Scherzer M. Scherzer	2	466	215	112	.657	457	3.16	3,407	12	5	0	2878.0	2,346	1,010	1,083	335	756	112	2	20	11,629	78	10.65	2.36	4.51	1.05	29.3	6.5	1.08	.287	3.39	7.34
8	Homer Bailey H. Bailey	2	245	81	86	.485	245	4.56	1,157	7	4	0	1401.2	1,455	710	756	175	463	56	0	31	6,039	42	7.43	2.97	2.50	1.12	19.2	7.7	1.37	.306	4.85	9.34
9	Tim Lincecum T. Lincecum	2	278	110	89	.553	270	3.74	1,736	10	7	1	1682.0	1,506	699	746	147	669	44	3	33	7,120	107	9.29	3.58	2.59	0.79	24.4	9.4	1.29	.300	3.99	8.06
10	Mark Buehrle M. Buehrle	2	518	214	160	.572	493	3.81	1,870	33	10	0	3283.1	3,472	1,391	1,542	361	734	79	6	49	13,705	27	5.13	2.01	2.55	0.99	13.6	5.4	1.28	.292	4.23	9.52
11	Hideo Nomo H. Nomo	2	323	123	109	.530	318	4.24	1,918	16	9	0	1976.1	1,768	932	993	251	908	38	2	31	8,462	110	8.73	4.13	2.11	1.14	22.7	10.7	1.35	.284	4.52	8.05
12	Randy Johnson R. Johnson	2	618	303	166	.646	603	3.29	4,875	100	37	2	4135.1	3,346	1,513	1,703	411	1,497	190	7	37	17,067	109	10.61	3.26	3.26	0.89	28.6	8.8	1.17	.291	3.71	7.28
13	Bob Forsch B. Forsch	2	498	168	136	.553	422	3.76	1,133	67	19	3	2794.2	2,777	1,169	1,319	216	832	45	19	84	11,715	93	3.65	2.68	1.36	0.70	9.7	7.1	1.29	.270	4.25	8.94
14	Steve Busby S. Busby	2	167	70	54	.565	150	3.72	659	53	7	0	1060.2	1,003	438	483	73	433	25	8	22	4,505	28	5.59	3.67	1.52	0.62	14.6	9.6	1.35	.281	4.10	8.51
15	Bill Stoneman B. Stoneman	2	245	54	85	.388	169	4.08	934	45	15	5	1236.1	1,182	561	617	120	602	43	28	46	5,396	36	6.80	4.38	1.55	0.87	17.3	11.2	1.44	.287	4.49	8.60
16	Don Wilson D. Wilson	2	266	104	92	.531	245	3.15	1,283	78	20	2	1748.0	1,479	612	699	119	640	47	10	32	7,305	77	6.61	3.30	2.00	0.61	17.6	8.8	1.21	.261	3.60	7.61
17	Ken Holtzman K. Holtzman	2	451	174	150	.537	410	3.49	1,601	127	31	3	2867.0	2,787	1,111	1,273	249	910	49	18	68	12,069	97	5.03	2.86	1.76	0.78	13.3	7.5	1.29	.274	4.00	8.75
18	Jim Maloney J. Maloney	2	302	134	84	.615	262	3.19	1,605	74	30	4	1849.0	1,518	655	729	138	810	36	18	37	7,746	125	7.81	3.94	1.98	0.67	20.7	10.5	1.26	.268	3.55	7.39
19	Jim Bunning J. Bunning	2	591	224	184	.549	519	3.27	2,855	151	40	16	3760.0	3,433	1,365	1,527	372	1,000	160	39	98	15,615	47	6.83	2.39	2.86	0.89	18.3	6.4	1.18	.273	3.66	8.22
20	Carl Erskine C. Erskine	2	335	122	78	.610	216	4.00	981	71	14	13	1718.2	1,638	764	830	199	646	16	61		7,279	38	5.14	3.38	1.52	1.04	13.5	8.9	1.33	.265	4.35	8.58
21	Allie Reynolds A. Reynolds	2	434	182	107	.630	309	3.30	1,423	137	36	48	2492.0	2,193	913	1,026	133	1,261	56	97		10,654	59	5.14	4.55	1.13	0.48	13.4	11.8	1.39	.265	3.71	7.92
22	Warren Spahn W. Spahn	2	750	363	245	.597	665	3.09	2,583	382	63	28	5243.2	4,833	1,801	2,018	434	1,432	41	67		21,555	78	4.43	2.46	1.80	0.74	12.0	6.6	1.19	.258	3.46	8.30
23	Virgil Trucks V. Trucks	2	517	177	135	.567	328	3.38	1,535	124	33	30	2682.1	2,416	1,007	1,125	189	1,088	49	114	20	11,381	64	5.15	3.65	1.41	0.63	13.5	9.6	1.31	.261	3.77	8.11
24	Johnny Vander Meer J. Vander Meer	2	346	119	121	.496	286	3.44	1,303	131	29	2	2103.2	1,800	804	915	99	1,132	23	28		9,061	37	5.57	4.84	1.15	0.42	14.4	12.5	1.39	.262	3.91	7.70
25	Dutch Leonard D. Leonard	2	331	139	114	.549	273	2.76	1,162	151	33	13	2190.1	2,021	672	853	55	676	73	48		9,095	60	4.77	2.78	1.72	0.23	12.8	7.4	1.23	.276	3.50	8.30