most mlb games played against one team by a team

The Chicago Cubs and the Pittsburgh Pirates are tied for the most games against a team, with 2,608 games.

Interpreted as:

most MLB regular-season games played against one team by a team

	TEAM	G	OPP	W%	W	L	AB	R	H	2B	3B	HR	BB	HBP	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Cubs	2,608	Pirates	.493	1,276	1,314		11,597								338			6,011		340	404	1,217		.324		.706
2	Pirates	2,608	Cubs	.507	1,314	1,276		11,455								410			5,939		356	445	1,146		.327		.708
3	Giants	2,580	Dodgers	.501	1,284	1,279		10,983								363			5,524		267	450	1,110		.319		.689
4	Dodgers	2,580	Giants	.499	1,279	1,284		11,074								397			5,533		349	456	1,045		.320		.692
5	Braves	2,547	Phillies	.524	1,327	1,205		11,754								289			5,959		279	346	1,016		.329		.719
6	Phillies	2,547	Braves	.476	1,205	1,327		10,920								290			5,486		285	383	1,091		.327		.703
7	Pirates	2,519	Cardinals	.511	1,274	1,221		11,406								301			5,928		362	398	1,308		.329		.712
8	Cardinals	2,519	Pirates	.489	1,221	1,274		11,057								405			5,907		360	451	1,298		.329		.711
9	Cubs	2,513	Cardinals	.510	1,273	1,221		10,965								313			5,920		321	387	1,257		.326		.706
10	Cardinals	2,513	Cubs	.490	1,221	1,273		10,986								418			5,965		355	405	1,159		.329		.713
11	Reds	2,496	Pirates	.497	1,230	1,247		11,029								300			5,602		330	393	1,085		.325		.709
12	Pirates	2,496	Reds	.503	1,247	1,230		10,887								305			5,608		308	297	1,047		.326		.708
13	Cubs	2,416	Reds	.505	1,208	1,186		10,922								274			5,869		286	338	1,003		.329		.718
14	Reds	2,416	Cubs	.495	1,186	1,208		10,498								327			5,599		294	346	948		.324		.703
15	Cubs	2,395	Phillies	.524	1,246	1,131		11,567								250			5,592		255	308	931		.332		.727
16	Phillies	2,395	Cubs	.476	1,131	1,246		10,897								310			5,256		262	358	874		.329		.713
17	Braves	2,394	Giants	.469	1,110	1,258		10,331								252			4,519		243	375	952		.316		.679
18	Giants	2,394	Braves	.531	1,258	1,110		11,170								278			5,102		247	357	1,042		.332		.721
19	Reds	2,383	Dodgers	.491	1,163	1,206		10,214								312			4,999		207	283	927		.318		.687
20	Dodgers	2,383	Reds	.509	1,206	1,163		10,529								316			5,016		266	345	1,025		.327		.703
21	Reds	2,373	Cardinals	.477	1,121	1,231		10,239								295			5,449		312	346	1,084		.324		.701
22	Cardinals	2,373	Reds	.523	1,231	1,121		10,652								328			5,806		303	356	1,041		.331		.720
23	Braves	2,333	Cubs	.459	1,063	1,252		9,928								277			4,367		227	252	893		.318		.681
24	Cubs	2,333	Braves	.541	1,252	1,063		10,822								245			4,778		185	276	894		.329		.711
25	White Sox	2,331	Twins	.512	1,186	1,129	79,191	10,204	20,745	3,394	769	1,365	7,147	603	1,654	371	88,823	29,772	5,528	1,544	338	208	1,124	.262	.326	.376	.702