Babe Ruth has launched the most career home runs by a player against a team, with 123 home runs versus the Tigers.

Interpreted as:

most home runs by a player against one team career

	NAME	HR	OPP	G	AB	R	H	2B	3B	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Babe Ruth B. Ruth	123	Tigers	360	1,222	338	413	89	19	342	318	8	189	22		1,562	909	231	14				.338	.477	.744	1.221
2	Babe Ruth B. Ruth	108	Athletics	347	1,181	318	416	66	12	323	281	5	194	15		1,487	830	186	20				.352	.479	.703	1.181
3	Willie Mays W. Mays	98	Dodgers	383	1,414	273	437	75	18	251	212	7	209	33	18	1,641	842	191	0	8	29	29	.309	.400	.595	.995
4	Babe Ruth B. Ruth	98	White Sox	354	1,188	303	404	74	18	331	287	4	173	16		1,491	808	190	12				.340	.470	.680	1.150
5	Hank Aaron H. Aaron	97	Reds	372	1,403	271	448	81	14	270	159	5	155	33	8	1,579	848	192	3	9	27	49	.319	.388	.604	.993
6	Babe Ruth B. Ruth	96	Browns	360	1,210	311	425	59	21	326	302	9	213	14		1,539	814	176	18				.351	.484	.673	1.157
7	Hank Aaron H. Aaron	95	Dodgers	391	1,444	246	436	79	11	247	199	5	175	21	3	1,664	822	185	6	10	49	42	.302	.386	.569	.955
8	Jimmie Foxx J. Foxx	93	Tigers	308	1,132	272	373	57	12	278	198	0	190	10		1,338	733	162	8			6	.330	.429	.648	1.077
9	Willie Mays W. Mays	92	Cubs	358	1,338	268	427	80	17	266	156	7	198	57	18	1,515	817	189	1	13	21	25	.319	.390	.611	1.000
10	Lou Gehrig L. Gehrig	92	Browns	310	1,138	291	404	75	23	305	250	8	95	13		1,410	801	190	14				.355	.474	.704	1.178
11	Babe Ruth B. Ruth	92	Indians	361	1,143	298	405	69	17	278	348	6	176	12		1,510	784	178	13				.354	.507	.686	1.193
12	Hank Aaron H. Aaron	91	Cardinals	354	1,374	248	423	79	8	290	157	4	166	16	11	1,551	791	178	4	12	38	28	.308	.378	.576	.953
13	Ted Williams T. Williams	91	Athletics	327	1,105	284	401	69	12	298	295	11	94	3	2	1,414	767	172	0	3	11	29	.363	.500	.694	1.194
14	Babe Ruth B. Ruth	90	Red Sox	293	1,030	285	347	61	13	272	240	4	139	22		1,290	704	164	16				.337	.464	.683	1.147
15	Stan Musial S. Musial	89	Giants	417	1,494	272	504	82	18	312	245	11	100	8	6	1,764	889	189	6	8	24	38	.337	.432	.595	1.027
16	Babe Ruth B. Ruth	89	Senators	349	1,191	276	395	75	34	294	239	6	198	21		1,457	805	198	21				.332	.446	.676	1.122
17	Ted Williams T. Williams	88	Tigers	332	1,167	280	386	75	6	283	284	5	111	5	0	1,463	737	169	2	5	11	28	.331	.462	.632	1.094
18	Barry Bonds B. Bonds	87	Padres	270	868	222	275	46	4	214	256	12	132	34	11	1,148	590	137	0	12	77	10	.317	.473	.680	1.153
19	Hank Aaron H. Aaron	87	Cubs	347	1,340	250	437	65	13	262	114	4	148	24	13	1,477	789	165	2	17	21	36	.326	.376	.589	.965
20	Jimmie Foxx J. Foxx	87	Browns	298	1,058	274	386	70	12	265	238	2	157	13		1,307	741	169	9			4	.365	.482	.700	1.183
21	Willie Mays W. Mays	83	Braves	377	1,335	242	392	58	11	229	184	6	169	32	13	1,538	721	152	0	13	16	33	.294	.378	.540	.918
22	Mel Ott M. Ott	83	Pirates	406	1,377	285	436	65	7	305	280	12	116	18		1,685	764	155	16			7	.317	.436	.555	.991
23	Ernie Banks E. Banks	82	Phillies	325	1,208	199	359	59	12	245	111	10	160	7	5	1,349	688	153	6	14	31	32	.297	.357	.570	.927
24	Mel Ott M. Ott	82	Phillies	384	1,349	304	428	76	10	342	284	12	110	20		1,666	770	168	21			5	.317	.440	.571	1.011
25	Ted Williams T. Williams	80	Orioles	310	1,064	269	398	80	6	289	291	4	97	5	1	1,360	730	166	0	1	8	25	.374	.510	.686	1.196