Andrew McCutchen has the most career games by an active player, with 2,150 games.

Interpreted as:

most regular-season games played by active MLB player

	NAME	G	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS	WRC	WRAA	WOBA	WRC+	BRAA
1	Andrew McCutchen A. McCutchen	2,150	7,949	1,249	2,173	433	50	322	1,105	1,127	92	1,790	220	89	9,243	3,672	805	3	72	69	138	.273	.367	.462	.829	1392	318.5	.359	127	296.2
2	Carlos Santana C. Santana	2,106	7,497	1,069	1,809	395	17	326	1,089	1,288	42	1,470	59	18	8,891	3,216	738	0	64	66	182	.241	.353	.429	.782	1220	182.6	.341	115	157.6
3	Freddie Freeman F. Freeman	2,049	7,618	1,307	2,284	513	31	347	1,246	1,016	108	1,647	98	31	8,804	3,900	891	0	62	136	160	.300	.387	.512	.899	1509	481.6	.382	142	448.4
4	Paul Goldschmidt P. Goldschmidt	1,956	7,223	1,217	2,094	454	23	363	1,197	1,059	50	1,901	170	35	8,388	3,683	840	0	56	117	169	.290	.382	.510	.892	1418	435.9	.379	139	391.9
5	Jose Altuve J. Altuve	1,847	7,399	1,169	2,261	433	31	232	821	606	76	1,053	318	92	8,155	3,452	696	26	48	46	197	.306	.362	.467	.829	1229	278.8	.357	129	283.7
6	Jason Heyward J. Heyward	1,807	6,131	874	1,568	305	41	185	724	704	62	1,229	125	43	6,935	2,510	531	6	32	27	103	.256	.337	.409	.746	865	58.7	.327	104	34
7	Manny Machado M. Machado	1,763	6,912	1,008	1,928	373	18	344	1,060	618	27	1,319	105	38	7,631	3,369	735	14	60	69	212	.279	.338	.487	.825	1112	216.5	.350	123	207.5
8	Nolan Arenado N. Arenado	1,706	6,504	957	1,851	395	33	344	1,144	563	41	1,053	29	23	7,189	3,344	772	5	76	79	193	.285	.342	.514	.856	1109	264	.360	118	158.9
9	Justin Turner J. Turner	1,695	5,583	801	1,587	347	9	198	819	579	136	988	46	13	6,364	2,546	554	5	61	18	143	.284	.362	.456	.818	950	201.1	.354	125	198.7
10	Bryce Harper B. Harper	1,681	6,038	1,099	1,694	374	24	341	992	1,058	46	1,558	146	50	7,212	3,139	739	13	57	133	136	.281	.389	.520	.909	1250	403.5	.384	142	365.4
11	Giancarlo Stanton G. Stanton	1,649	6,025	907	1,551	305	11	429	1,103	776	53	1,963	42	15	6,893	3,165	745	0	39	88	153	.257	.345	.525	.871	1093	294.9	.368	135	288.9
12	DJ LeMahieu	1,628	6,004	883	1,738	275	39	124	651	561	31	1,013	93	49	6,680	2,463	438	37	47	24	185	.289	.351	.410	.761	874	88.7	.331	100	6.2
13	Salvador Perez S. Perez	1,580	5,987	664	1,595	294	11	275	930	250	84	1,202	6	1	6,373	2,736	580	0	52	38	184	.266	.303	.457	.760	788	47.7	.324	102	19.2
14	Nick Castellanos N. Castellanos	1,569	5,968	768	1,634	380	41	236	863	409	51	1,505	38	22	6,475	2,804	657	0	47	19	133	.274	.323	.470	.793	887	121.9	.338	111	93.5
15	Xander Bogaerts X. Bogaerts	1,558	5,953	896	1,716	362	18	186	790	558	55	1,199	110	22	6,627	2,672	566	5	56	22	151	.288	.352	.449	.801	945	163.3	.345	115	125.7
16	Mike Trout M. Trout	1,545	5,610	1,137	1,665	312	55	387	972	992	101	1,518	214	38	6,760	3,248	754	0	57	122	69	.297	.408	.579	.987	1326	541.5	.414	168	544.2
17	Marcus Semien M. Semien	1,529	5,995	912	1,520	308	35	240	751	590	22	1,234	128	40	6,649	2,618	583	7	35	8	97	.254	.321	.437	.758	852	64.1	.326	108	67.6
18	Eugenio Suárez E. Suárez	1,499	5,329	758	1,320	238	15	286	851	598	90	1,649	33	19	6,082	2,446	539	9	56	15	121	.248	.331	.459	.790	839	116.7	.339	112	88.5
19	Christian Yelich C. Yelich	1,494	5,636	959	1,614	309	35	209	771	786	46	1,408	211	36	6,500	2,620	553	5	27	55	118	.286	.377	.465	.841	1018	254.1	.363	129	236.7
20	Marcell Ozuna M. Ozuna	1,493	5,637	776	1,539	264	21	280	891	536	23	1,368	29	14	6,226	2,685	565	1	29	18	143	.273	.337	.476	.813	902	171.1	.348	121	159.2
21	José Ramírez J. Ramírez	1,477	5,472	910	1,525	368	40	260	878	609	38	740	248	57	6,194	2,753	668	19	56	90	78	.279	.352	.503	.855	959	223.8	.359	129	216.1
22	Starling Marte S. Marte	1,450	5,504	846	1,568	279	55	155	641	323	162	1,210	356	98	6,033	2,422	489	21	23	18	114	.285	.341	.440	.782	820	115.6	.339	115	109.3
23	Mookie Betts M. Betts	1,406	5,589	1,087	1,637	374	39	275	843	689	50	865	190	39	6,384	2,914	688	4	52	33	74	.293	.372	.521	.894	1091	332.9	.379	139	304
24	Francisco Lindor F. Lindor	1,402	5,551	913	1,526	308	26	253	784	531	67	1,007	187	46	6,239	2,645	587	31	59	34	101	.275	.342	.476	.819	911	167.1	.348	121	156.1
25	George Springer G. Springer	1,331	5,137	886	1,352	229	23	263	724	618	77	1,226	106	40	5,865	2,416	515	2	31	11	109	.263	.349	.470	.819	875	180.3	.353	127	190.3