Albert Pujols has launched the most career home runs in the 1st inning, with 154 home runs.

Interpreted as:

most career home runs by a player in the 1st inning

	NAME	HR	G	AB	H	2B	3B	RBI	BB	HBP	SO	PA	TB	XBH	SH	SF	IBB	AVG	OBP	SLG	OPS
1	Albert Pujols A. Pujols	154	2,554	2,257	662	147	2	469	244	18	275	2,557	1,275	303	0	38	20	.293	.361	.565	.926
2	Barry Bonds B. Bonds	133	2,206	1,708	546	109	13	403	456	25	264	2,209	1,080	255	0	20	95	.320	.465	.632	1.097
3	Alex Rodriguez A. Rodriguez	122	2,227	1,890	544	97	2	379	273	39	445	2,233	1,011	221	8	23	1	.288	.385	.535	.920
4	Gary Sheffield G. Sheffield	118	2,172	1,821	548	82	9	394	293	30	268	2,173	1,002	209	1	28	5	.301	.401	.550	.951
5	Ken Griffey Jr. K. Griffey Jr.	111	2,293	1,957	551	99	4	370	281	23	406	2,294	991	214	0	33	8	.282	.373	.506	.879
6	Frank Thomas F. Thomas	109	1,993	1,610	469	93	3	349	337	15	266	1,997	895	205	0	35	9	.291	.411	.556	.967
7	Sammy Sosa S. Sosa	106	1,613	1,437	384	61	2	293	150	10	423	1,617	767	169	0	20	8	.267	.336	.534	.870
8	Mike Trout M. Trout	99	1,498	1,300	379	68	11	175	171	24	355	1,501	766	178	0	6	1	.292	.382	.589	.972
9	Mark McGwire M. McGwire	98	1,112	886	248	38	1	301	193	14	246	1,115	582	137	0	22	10	.280	.408	.657	1.065
10	Paul Goldschmidt P. Goldschmidt	92	1,724	1,484	433	82	3	255	210	12	419	1,727	797	177	0	17	4	.292	.380	.537	.917
11	Miguel Cabrera M. Cabrera	92	2,156	1,882	567	100	2	364	227	16	402	2,158	947	194	1	32	11	.301	.376	.503	.879
12	David Ortiz D. Ortiz	85	1,628	1,368	409	97	3	337	245	4	316	1,630	767	185	0	13	8	.299	.404	.561	.964
13	Rafael Palmeiro R. Palmeiro	85	2,053	1,780	515	105	8	369	222	21	230	2,055	891	198	0	32	9	.289	.369	.501	.869
14	Ryan Braun R. Braun	83	1,576	1,426	410	100	6	253	126	16	294	1,577	771	189	0	9	0	.288	.350	.541	.891
15	Eddie Murray E. Murray	83	1,805	1,562	444	86	1	422	208	1	236	1,807	781	170	0	36	21	.284	.361	.500	.861
16	Nolan Arenado N. Arenado	82	1,225	1,098	343	80	8	281	107	6	180	1,225	685	170	0	14	2	.312	.372	.624	.996
17	Rickey Henderson R. Henderson	82	2,886	2,491	688	118	17	90	399	19	416	2,909	1,086	217	0	0	0	.276	.380	.436	.816
18	Chipper Jones C. Jones	81	2,170	1,806	527	108	6	321	337	4	321	2,172	890	195	0	25	4	.292	.400	.493	.892
19	Craig Biggio C. Biggio	81	2,554	2,291	659	148	15	129	191	56	364	2,565	1,080	244	21	6	0	.288	.356	.471	.828
20	Mike Schmidt M. Schmidt	81	1,625	1,357	356	72	12	317	225	16	345	1,627	695	165	3	26	6	.262	.368	.512	.880
21	Alfonso Soriano A. Soriano	80	1,262	1,185	337	80	4	164	59	19	258	1,272	665	164	0	9	0	.284	.326	.561	.887
22	Freddie Freeman F. Freeman	79	1,799	1,565	482	112	1	230	196	27	348	1,800	833	192	0	12	1	.308	.392	.532	.924
23	Carlos Beltran C. Beltran	79	2,068	1,837	492	96	16	296	187	9	352	2,071	857	191	8	30	0	.268	.333	.467	.800
24	Jim Thome J. Thome	76	1,315	1,031	285	52	1	294	259	8	317	1,316	567	129	0	18	11	.276	.419	.550	.969
25	Jose Canseco J. Canseco	76	1,528	1,288	335	66	2	259	209	16	385	1,528	633	144	0	15	2	.260	.366	.491	.858