Salvador Perez and Vladimir Guerrero Jr. were tied for the most homers in 2021, with 48 home runs.

	NAME	HR	SEASON	TM	G	AB	R	H	2B	3B	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS	WRC	WRAA	WOBA	WRC+	BRAA
1	Salvador Perez S. Perez	48	2021	KCR	161	620	88	169	24	0	121	28	13	170	1	0	665	337	72	0	4	4	14	.273	.316	.544	.859	105	24.6	.359	125	20.4
2	Vladimir Guerrero Jr. V. Guerrero Jr.	48	2021	TOR	161	604	123	188	29	1	111	86	6	110	4	1	698	363	78	0	2	7	20	.311	.401	.601	1.002	145	60.4	.419	166	56.1
3	Shohei Ohtani S. Ohtani	46	2021	LAA	155	537	103	138	26	8	100	96	4	189	26	10	639	318	80	0	2	20	7	.257	.372	.592	.965	119	41.8	.393	150	39.4
4	Marcus Semien M. Semien	45	2021	TOR	162	652	115	173	39	2	102	66	3	146	15	1	724	351	86	0	3	0	9	.265	.334	.538	.873	120	31.9	.368	131	27.4
5	Fernando Tatis Jr. F. Tatis Jr.	42	2021	SDP	130	478	99	135	31	0	97	62	2	153	25	4	546	292	73	0	4	6	5	.282	.364	.611	.975	106	39.9	.403	158	40.4
6	Mitch Haniger M. Haniger	39	2021	SEA	157	620	110	157	23	2	100	54	9	169	1	0	691	301	64	0	8	2	12	.253	.318	.485	.804	98	14.5	.340	120	16.9
7	Aaron Judge A. Judge	39	2021	NYY	148	550	89	158	24	0	98	75	3	158	6	1	633	299	63	0	5	2	16	.287	.373	.544	.916	115	38	.387	150	38.7
8	Matt Olson M. Olson	39	2021	OAK	156	565	101	153	35	0	111	88	9	113	4	1	673	305	74	0	11	12	17	.271	.371	.540	.911	117	35.7	.379	147	38.9
9	Brandon Lowe B. Lowe	39	2021	TBR	149	535	97	132	31	0	99	68	9	167	7	1	615	280	70	0	3	4	2	.247	.340	.523	.863	99	24.9	.363	137	27.8
10	Rafael Devers R. Devers	38	2021	BOS	156	591	101	165	37	1	113	62	7	143	5	5	664	318	76	0	4	7	13	.279	.352	.538	.890	113	32.2	.373	133	26.5
11	Adam Duvall A. Duvall	38	2021	TOT	146	513	67	117	17	2	113	35	4	174	5	0	555	252	57	0	3	1	7	.228	.281	.491	.772	72	4.5	.324	101	0.8
12	Joey Gallo J. Gallo	38	2021	TOT	153	498	90	99	13	1	77	111	6	213	6	0	616	228	52	0	1	5	6	.199	.351	.458	.808	92	17.4	.348	121	16.2
13	Pete Alonso P. Alonso	37	2021	NYM	152	561	81	147	27	3	94	60	12	127	3	0	637	291	67	0	4	6	20	.262	.344	.519	.863	103	25.4	.363	131	25.3
14	Max Muncy M. Muncy	36	2021	LAD	144	497	95	124	26	2	94	83	11	120	2	1	592	262	64	0	1	5	7	.249	.368	.527	.895	103	31.5	.379	140	29.9
15	José Ramírez J. Ramírez	36	2021	CLE	152	552	111	147	32	5	103	72	7	87	27	4	636	297	73	0	5	10	13	.266	.355	.538	.893	107	30.2	.372	140	30.9
16	Joey Votto J. Votto	36	2021	CIN	129	448	73	119	23	1	99	77	4	127	1	0	533	252	60	0	4	6	7	.266	.375	.563	.938	98	33.9	.391	140	27.4
17	Bryce Harper B. Harper	35	2021	PHI	141	488	101	151	42	1	84	100	5	134	13	3	599	300	78	2	4	14	12	.309	.429	.615	1.044	130	57.7	.431	171	54
18	Kyle Seager K. Seager	35	2021	SEA	159	603	73	128	29	1	101	59	4	161	3	1	670	264	65	0	4	2	7	.212	.285	.438	.723	77	-3.8	.308	98	-1.4
19	Giancarlo Stanton G. Stanton	35	2021	NYY	139	510	64	139	19	0	97	63	3	157	0	0	579	263	54	0	3	1	22	.273	.354	.516	.870	97	26.4	.370	138	27
20	Nolan Arenado N. Arenado	34	2021	STL	157	593	81	151	34	3	105	50	3	96	2	0	653	293	71	0	7	8	20	.255	.312	.494	.807	91	11.6	.336	112	9.9
21	Nick Castellanos N. Castellanos	34	2021	CIN	138	531	95	164	38	1	100	41	7	121	3	1	585	306	73	0	6	5	16	.309	.362	.576	.939	108	37.2	.391	140	30
22	Tyler O'Neill T. O'Neill	34	2021	STL	138	482	89	138	26	2	80	38	13	168	15	4	537	270	62	0	4	0	8	.286	.352	.560	.912	96	30.8	.384	143	29.4
23	Jorge Polanco J. Polanco	33	2021	MIN	152	588	97	158	35	2	98	45	5	118	11	6	644	296	70	0	6	0	4	.269	.323	.503	.826	97	18.5	.349	123	18.4
24	Mike Zunino M. Zunino	33	2021	TBR	109	333	64	72	11	2	62	34	7	132	0	0	375	186	46	0	1	0	7	.216	.301	.559	.860	59	13.7	.358	134	15.4
25	Ryan Mountcastle R. Mountcastle	33	2021	BAL	144	534	77	136	23	1	89	41	4	161	4	3	586	260	57	0	7	2	12	.255	.309	.487	.796	81	10	.335	111	7.8