Between the 2000 and 2009 seasons, Alex Rodriguez smashed the most homers, with 435 homers.

	NAME	HR	G	AB	R	H	2B	3B	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS	WRC	WRAA	WOBA	WRC+	BRAA
1	Alex Rodriguez A. Rodriguez	435	1,524	5,732	1,190	1,740	285	16	1,243	850	125	1,243	179	37	6,768	3,362	736	0	61	82	149	.304	.401	.587	.988	1325	491.3	.416	154	459.7
2	Jim Thome J. Thome	368	1,368	4,629	877	1,255	231	8	986	973	37	1,431	3	9	5,681	2,606	607	0	42	112	81	.271	.399	.563	.962	1057	355	.404	145	321.6
3	Albert Pujols A. Pujols	366	1,399	5,146	1,071	1,717	387	14	1,112	811	69	570	61	30	6,082	3,230	767	1	55	198	180	.334	.427	.628	1.055	1295	551.8	.437	169	537.6
4	Manny Ramirez M. Ramirez	348	1,358	4,931	933	1,562	328	11	1,106	828	69	1,085	10	9	5,874	2,956	687	0	46	174	148	.317	.419	.599	1.018	1190	466.7	.424	158	433.5
5	Carlos Delgado C. Delgado	324	1,368	4,951	863	1,416	326	12	1,045	796	126	1,121	9	3	5,938	2,738	662	0	65	151	108	.286	.394	.553	.947	1069	335.2	.397	141	309.5
6	Barry Bonds B. Bonds	317	986	2,871	772	925	178	12	697	1,128	53	427	54	9	4,072	2,078	507	0	20	390	49	.322	.517	.724	1.241	1059	552.8	.490	203	542
7	Adam Dunn A. Dunn	316	1,290	4,417	780	1,101	230	8	777	913	62	1,433	59	20	5,417	2,295	554	2	23	97	65	.249	.383	.520	.903	913	251.7	.384	131	211.4
8	Vladimir Guerrero V. Guerrero	315	1,432	5,415	929	1,751	324	30	1,037	569	66	670	147	67	6,094	3,080	669	0	44	213	190	.323	.392	.569	.960	1107	355.6	.399	142	328.3
9	Lance Berkman L. Berkman	309	1,473	5,169	959	1,553	357	25	1,026	968	61	1,030	74	39	6,248	2,887	691	1	49	130	110	.300	.413	.559	.972	1192	424.5	.410	148	384.5
10	Andruw Jones A. Jones	308	1,413	5,219	852	1,340	263	20	917	610	69	1,174	69	30	5,955	2,567	591	0	57	47	138	.257	.339	.492	.831	858	121.5	.354	112	93.3
11	David Ortiz D. Ortiz	307	1,340	4,825	831	1,365	357	14	1,016	749	24	1,004	9	5	5,653	2,671	678	2	53	87	106	.283	.378	.554	.932	992	296.8	.392	136	258.1
12	Jason Giambi J. Giambi	303	1,305	4,257	775	1,171	224	5	912	942	138	965	13	5	5,387	2,314	532	0	50	69	88	.275	.418	.544	.961	1032	367.6	.410	152	358.4
13	Paul Konerko P. Konerko	295	1,477	5,357	790	1,491	274	3	935	599	71	874	7	1	6,082	2,656	572	0	55	50	194	.278	.355	.496	.851	926	176.8	.364	118	138.4
14	Carlos Lee C. Lee	291	1,513	5,751	873	1,674	343	11	1,019	488	36	744	111	39	6,352	2,912	645	2	75	47	153	.291	.346	.506	.852	957	174.2	.362	118	142.7
15	Alfonso Soriano A. Soriano	289	1,313	5,403	859	1,505	334	24	759	338	65	1,184	257	70	5,852	2,754	647	8	38	52	64	.279	.326	.510	.836	839	122.9	.354	112	90.1
16	Jermaine Dye J. Dye	274	1,372	5,110	806	1,406	284	16	871	503	57	1,025	39	16	5,722	2,544	574	1	51	34	142	.275	.344	.498	.841	848	142.6	.359	114	106.2
17	Troy Glaus T. Glaus	274	1,207	4,282	733	1,108	237	10	777	705	36	1,083	50	28	5,059	2,187	521	0	36	37	110	.259	.365	.511	.876	816	191.2	.375	127	174
18	Chipper Jones C. Jones	273	1,387	4,935	916	1,535	306	20	921	884	14	768	59	25	5,887	2,700	599	0	54	127	138	.311	.413	.547	.960	1104	377.9	.406	147	354.2
19	Gary Sheffield G. Sheffield	273	1,268	4,572	857	1,344	226	11	869	718	63	621	97	33	5,399	2,411	510	0	46	52	129	.294	.394	.527	.921	959	293.6	.394	141	284.9
20	Sammy Sosa S. Sosa	273	945	3,524	634	995	173	10	726	501	23	937	10	8	4,088	2,007	456	0	40	90	81	.282	.372	.570	.941	721	214	.391	137	198.1
21	Derrek Lee D. Lee	270	1,448	5,254	854	1,536	339	26	841	695	52	1,164	94	41	6,048	2,737	635	2	45	67	146	.292	.378	.521	.899	1017	274.1	.383	131	239.9
22	Pat Burrell P. Burrell	265	1,428	4,947	700	1,257	269	15	891	842	28	1,392	7	1	5,864	2,351	549	0	47	49	110	.254	.363	.475	.838	880	159.1	.362	117	127.2
23	Richie Sexson R. Sexson	264	1,179	4,264	647	1,107	229	9	792	548	45	1,152	10	9	4,885	2,146	502	0	28	31	120	.260	.348	.503	.851	743	139.3	.364	120	126.1
24	Jim Edmonds J. Edmonds	261	1,216	3,968	743	1,113	253	13	768	700	33	1,111	39	26	4,757	2,175	527	7	49	69	71	.280	.389	.548	.937	851	262.2	.395	140	246.3
25	Todd Helton T. Helton	260	1,466	5,305	1,017	1,756	431	27	981	1,001	39	741	26	17	6,409	3,021	718	2	62	164	130	.331	.436	.569	1.006	1299	508.8	.424	144	366.3