Trevor Rosenthal has the most saves for the Cardinals in a season, with 48 saves in 2015.

	NAME	SV	SEASON	TM	G	W	L	W%	GS	ERA	SO	CG	SHO	IP	H	ER	R	HR	BB	HBP	GF	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	ERA-	FIP	FIP-	H/9	PRAA
1	Trevor Rosenthal T. Rosenthal	48	2015	STL	68	2	4	.333	0	2.10	83	0	0	68.2	62	16	16	3	25	1	57	3	287	7	10.88	3.28	3.32	0.39	28.9	8.7	1.27	.337	2.10	55	2.41	63	8.13	10.9
2	Ryan Helsley R. Helsley	47	2024	STL	65	7	4	.636	0	2.04	79	0	0	66.1	50	15	19	3	23	0	62	3	266	1	10.72	3.12	3.43	0.41	29.7	8.6	1.10	.292	2.58	50	2.41	61	6.78	11.8
3	Jason Isringhausen J. Isringhausen	47	2004	STL	74	4	2	.667	0	2.87	71	0	0	75.1	55	24	27	5	23	2	66	4	308	1	8.48	2.75	3.09	0.60	23.1	7.5	1.04	.242	3.23	68	3.01	70	6.57	11
4	Lee Smith L. Smith	47	1991	STL	67	6	3	.667	0	2.34	67	0	0	73.0	70	19	19	5	13	0	61	5	300	1	8.26	1.60	5.15	0.62	22.3	4.3	1.14	.302	2.34	64	2.44	66	8.63	10.4
5	Trevor Rosenthal T. Rosenthal	45	2014	STL	72	2	6	.250	0	3.20	87	0	0	70.1	57	25	25	2	42	4	59	5	308	1	11.13	5.37	2.07	0.26	28.2	13.6	1.41	.318	3.20	89	2.99	82	7.29	5.2
6	Bruce Sutter B. Sutter	45	1984	STL	71	5	7	.417	0	1.54	77	0	0	122.2	109	21	26	9	23	1	63	4	477	2	5.65	1.69	3.35	0.66	16.1	4.8	1.08	.272	1.91	43	3.05	87	8.00	6
7	Lee Smith L. Smith	43	1993	STL	55	2	4	.333	0	4.50	49	0	0	50.0	49	25	25	11	9	0	48	1	206	1	8.82	1.62	5.44	1.98	23.8	4.4	1.16	.277	4.50	114	4.42	110	8.82	-2.3
8	Lee Smith L. Smith	43	1992	STL	70	4	9	.308	0	3.12	60	0	0	75.0	62	26	28	4	26	0	55	4	310	2	7.20	3.12	2.31	0.48	19.4	8.4	1.17	.264	3.36	90	2.91	83	7.44	5
9	Jason Motte J. Motte	42	2012	STL	67	4	5	.444	0	2.75	86	0	0	72.0	49	22	23	9	17	2	58	1	279	0	10.75	2.13	5.06	1.13	30.8	6.1	0.92	.242	2.88	71	3.11	81	6.13	6
10	Jason Isringhausen J. Isringhausen	39	2005	STL	63	1	2	.333	0	2.14	51	0	0	59.0	43	14	14	4	27	1	52	5	245	2	7.78	4.12	1.89	0.61	20.8	11.0	1.19	.241	2.14	52	3.59	86	6.56	3.8
11	Ryan Franklin R. Franklin	38	2009	STL	62	4	3	.571	0	1.92	44	0	0	61.0	49	13	13	2	24	1	54	3	250	1	6.49	3.54	1.83	0.30	17.6	9.6	1.20	.263	1.92	47	3.30	80	7.23	5.5
12	Edward Mujica E. Mujica	37	2013	STL	65	2	1	.667	0	2.78	46	0	0	64.2	60	20	20	9	5	1	49	1	255	0	6.40	0.70	9.20	1.25	18.0	2.0	1.01	.263	2.78	76	3.71	100	8.35	0.1
13	Dennis Eckersley D. Eckersley	36	1997	STL	57	1	5	.167	0	3.91	45	0	0	53.0	49	23	24	9	8	2	47	0	218	2	7.64	1.36	5.63	1.53	20.6	3.7	1.08	.260	4.08	94	4.18	98	8.32	0.6
14	Tom Henke T. Henke	36	1995	STL	52	1	1	.500	0	1.82	48	0	0	54.1	42	11	11	2	18	0	47	0	221	1	7.95	2.98	2.67	0.33	21.7	8.1	1.10	.261	1.82	44	2.80	68	6.96	8.1
15	Todd Worrell T. Worrell	36	1986	STL	74	9	10	.474	0	2.08	73	0	0	103.2	86	24	29	9	41	1	60	16	430	1	6.34	3.56	1.78	0.78	17.0	9.5	1.23	.252	2.52	57	3.70	102	7.47	-1
16	Bruce Sutter B. Sutter	36	1982	STL	70	9	8	.529	0	2.90	61	0	0	102.1	88	33	38	8	34	3	58	13	424	5	5.36	2.99	1.79	0.70	14.4	8.0	1.19	.252	3.34	80	3.62	103	7.74	-1.5
17	Jason Isringhausen J. Isringhausen	33	2006	STL	59	4	8	.333	0	3.55	52	0	0	58.1	47	23	25	10	38	3	51	3	257	3	8.02	5.86	1.37	1.54	20.2	14.8	1.46	.240	3.86	82	5.69	128	7.25	-8.4
18	Todd Worrell T. Worrell	33	1987	STL	75	8	6	.571	0	2.66	92	0	0	94.2	86	28	29	8	34	0	54	11	395	1	8.75	3.23	2.71	0.76	23.3	8.6	1.27	.299	2.76	66	3.09	78	8.18	9.2
19	Jason Isringhausen J. Isringhausen	32	2007	STL	63	4	0	1.000	0	2.48	54	0	0	65.1	42	18	21	4	28	2	54	3	267	3	7.44	3.86	1.93	0.55	20.2	10.5	1.07	.212	2.89	58	3.75	85	5.79	4.7
20	Jason Isringhausen J. Isringhausen	32	2002	STL	60	3	2	.600	0	2.48	68	0	0	65.1	46	18	22	0	18	1	51	1	257	0	9.37	2.48	3.78	0.00	26.5	7.0	0.98	.271	3.03	62	1.74	42	6.34	17.4
21	Todd Worrell T. Worrell	32	1988	STL	68	5	9	.357	0	3.00	78	0	0	90.0	69	30	32	7	34	1	54	14	366	6	7.80	3.40	2.29	0.70	21.3	9.3	1.14	.252	3.20	86	3.20	92	6.90	2.7
22	Dennis Eckersley D. Eckersley	30	1996	STL	63	0	6	.000	0	3.30	49	0	0	60.0	65	22	26	8	6	4	53	2	251	0	7.35	0.90	8.17	1.20	19.5	2.4	1.18	.310	3.90	79	3.76	88	9.75	3.5
23	Alex Reyes A. Reyes	29	2021	STL	69	10	8	.556	0	3.24	95	0	0	72.1	46	26	32	9	52	2	54	1	317	10	11.82	6.47	1.83	1.12	30.0	16.4	1.35	.233	3.98	79	4.39	106	5.72	-2
24	Dave Veres D. Veres	29	2000	STL	71	3	5	.375	0	2.85	67	0	0	75.2	65	24	26	6	25	6	61	2	310	3	7.97	2.97	2.68	0.71	21.6	8.1	1.19	.286	3.09	62	3.61	75	7.73	9.9
25	Bud Norris B. Norris	28	2018	STL	64	3	6	.333	0	3.59	67	0	0	57.2	51	23	27	8	21	5	42	3	245	9	10.46	3.28	3.19	1.25	27.3	8.6	1.25	.299	4.21	93	3.99	100	7.96	-0.1