Michail Antonio has 3 goals and 3 assists in 16 appearances versus Southampton in the Premier League in his career.
| NAME | DATE | CLUB | OPP | MIN | G | A | XG | XA | PK | FK | SH | SOT | WOOD | TCH | TCH-BOX | OFF | FOUL | YC | RC | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | M. Antonio | 12/28/2015 |  West Ham | vs |  Southampton | 90 | 1 | 1 | 0 | 0 | 3 | 1 | 1 | 40 | 0 | 1 | 0 | 0 | 0 | ||
| 2 | | M. Antonio | 2/6/2016 | West Ham | @ | Southampton | 73 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 47 | 0 | 1 | 0 | 0 | 0 | ||
| 3 | | M. Antonio | 9/25/2016 | West Ham | vs | Southampton | 90 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 44 | 5 | 0 | 1 | 0 | 0 | ||
| 4 | | M. Antonio | 2/4/2017 | West Ham | @ | Southampton | 90 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 50 | 1 | 3 | 0 | 0 | 0 | ||
| 5 | | M. Antonio | 8/19/2017 | West Ham | @ | Southampton | 68 | 0 | 0 | 0 | 0 | 4 | 3 | 0 | 32 | 4 | 0 | 1 | 0 | 0 | ||
| 6 | | M. Antonio | 3/31/2018 | West Ham | vs | Southampton | 9 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 9 | 1 | 0 | 0 | 0 | 0 | ||
| 7 | | M. Antonio | 12/27/2018 | West Ham | @ | Southampton | 90 | 0 | 1 | 0 | 0 | 3 | 0 | 0 | 104 | 1 | 0 | 1 | 0 | 0 | ||
| 8 | | M. Antonio | 5/4/2019 | West Ham | vs | Southampton | 90 | 0 | 0 | 0 | 0 | 2 | 2 | 0 | 52 | 4 | 0 | 0 | 0 | 0 | ||
| 9 | | M. Antonio | 12/14/2019 | West Ham | @ | Southampton | 90 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 61 | 5 | 0 | 4 | 0 | 0 | ||
| 10 | | M. Antonio | 2/29/2020 | West Ham | vs | Southampton | 90 | 1 | 1 | 0 | 0 | 2 | 2 | 0 | 44 | 8 | 0 | 1 | 0 | 0 | ||
| 11 | | M. Antonio | 12/29/2020 | West Ham | @ | Southampton | 13 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 9 | 0 | 0 | 0 | 0 | 0 | ||
| 12 | | M. Antonio | 5/23/2021 | West Ham | vs | Southampton | 69 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 36 | 5 | 0 | 0 | 0 | 0 | ||
| 13 | | M. Antonio | 9/11/2021 | West Ham | @ | Southampton | 89 | 0 | 0 | 0.15 | 0.01 | 0 | 0 | 2 | 1 | 0 | 45 | 4 | 1 | 3 | 2 | 1 |
| 14 | | M. Antonio | 12/26/2021 | West Ham | vs | Southampton | 45 | 1 | 0 | 0.91 | 0.01 | 0 | 0 | 3 | 2 | 0 | 22 | 4 | 0 | 0 | 0 | 0 |
| 15 | | M. Antonio | 10/16/2022 | West Ham | @ | Southampton | 3 | 0 | 0 | 0.00 | 0.00 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 |
| 16 | | M. Antonio | 4/2/2023 | West Ham | vs | Southampton | 25 | 0 | 0 | 0.19 | 0.01 | 0 | 0 | 1 | 0 | 0 | 16 | 5 | 0 | 0 | 0 | 0 |
| Total | 1,024 | 3 | 3 | 0 | 0 | 26 | 11 | 1 | 613 | 47 | 6 | 11 | 2 | 1 |
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