Mario Balotelli had 5 goals in 20 appearances in the Premier League against Big Six opponents in his career.

Mario Balotelli stats against the big six in his career

	NAME	DATE	CLUB		OPP	MIN	G	PK	FK	SH	SOT	WOOD	TCH	TCH-BOX	OFF	FOUL	YC	RC
1	Mario Balotelli M. Balotelli	10/24/2010	Man City	vs	Arsenal	18	0	0									0	0
2	Mario Balotelli M. Balotelli	3/20/2011	Man City	@	Chelsea	9	0	0									0	0
3	Mario Balotelli M. Balotelli	4/11/2011	Man City	@	Liverpool	67	0	0									0	0
4	Mario Balotelli M. Balotelli	10/23/2011	Man City	@	Man United	70	2	0									1	0
5	Mario Balotelli M. Balotelli	11/27/2011	Man City	@	Liverpool	17	0	0									2	1
6	Mario Balotelli M. Balotelli	12/12/2011	Man City	@	Chelsea	90	1	0									0	0
7	Mario Balotelli M. Balotelli	12/18/2011	Man City	vs	Arsenal	72	0	0									0	0
8	Mario Balotelli M. Balotelli	1/22/2012	Man City	vs	Tottenham	25	1	1									1	0
9	Mario Balotelli M. Balotelli	3/21/2012	Man City	vs	Chelsea	45	0	0									0	0
10	Mario Balotelli M. Balotelli	4/8/2012	Man City	@	Arsenal	89	0	0									2	1
11	Mario Balotelli M. Balotelli	8/26/2012	Man City	@	Liverpool	62	0	0									0	0
12	Mario Balotelli M. Balotelli	9/23/2012	Man City	vs	Arsenal	5	0	0									0	0
13	Mario Balotelli M. Balotelli	11/25/2012	Man City	@	Chelsea	4	0	0									1	0
14	Mario Balotelli M. Balotelli	12/9/2012	Man City	vs	Man United	52	0	0									0	0
15	Mario Balotelli M. Balotelli	1/13/2013	Man City	@	Arsenal	2	0	0									0	0
16	Mario Balotelli M. Balotelli	8/31/2014	Liverpool	@	Tottenham	61	0	0	0	5	1	0	34	0	0	4	0	0
17	Mario Balotelli M. Balotelli	11/8/2014	Liverpool	vs	Chelsea	79	0	0	0	1	0	0	30	0	4	1	1	0
18	Mario Balotelli M. Balotelli	12/14/2014	Liverpool	@	Man United	45	0	0	0	7	4	1	22	0	1	4	1	0
19	Mario Balotelli M. Balotelli	2/10/2015	Liverpool	vs	Tottenham	16	1	0	0	1	1	0	11	0	0	2	0	0
20	Mario Balotelli M. Balotelli	3/22/2015	Liverpool	vs	Man United	24	0	0	0	1	0	0	14	0	0	1	1	0
	Total					852	5	1									10	2