Manchester United had their highest goal differential in a Premier League match versus Man City on November 10, 1994, with a differential of 5 goals.

man united biggest win in a game vs man city

	CLUB	GD	DATE		OPP	RESULT	G	SH	SOT	PASS	PASS-ATT	POSS%	FOUL	YC	RC	SUBS
1	Man United	5	11/10/1994	vs	Man City	W 5-0	5							1	0	1
2	Man United	3	2/11/1995	@	Man City	W 3-0	3							1	0	2
3	Man United	2	3/7/2021	@	Man City	W 2-0	2	8	6	283	364	33.9	12	3	0	3
4	Man United	2	3/8/2020	vs	Man City	W 2-0	2	12	6	215	292	27.7	11	2	0	3
5	Man United	2	4/12/2015	vs	Man City	W 4-2	4	11	7	442	546	58.6	9	0	0	3
6	Man United	2	5/10/2009	vs	Man City	W 2-0	2	16	5		417	47.1	11	1	0	3
7	Man United	2	12/9/2006	vs	Man City	W 3-1	3	22	10		466	53.5	15	1	0	1
8	Man United	2	2/13/2005	@	Man City	W 2-0	2							3	0	3
9	Man United	2	12/13/2003	vs	Man City	W 3-1	3							0	0	1
10	Man United	2	4/23/1994	vs	Man City	W 2-0	2							3	0	1
11	Man United	1	12/15/2024	@	Man City	W 2-1	2	10	3	420	473	48.4	14	1	0	5
12	Man United	1	1/14/2023	vs	Man City	W 2-1	2	8	4	234	318	29.7	15	3	0	5
13	Man United	1	12/7/2019	@	Man City	W 2-1	2	11	7	200	268	28.1	10	2	0	3
14	Man United	1	4/7/2018	@	Man City	W 3-2	3	5	4	244	318	35.2	9	3	0	3
15	Man United	1	3/20/2016	@	Man City	W 1-0	1	5	4	304	406	45.5	12	1	0	3
16	Man United	1	12/9/2012	@	Man City	W 3-2	3	10	3		372	43.8	9	3	0	3
17	Man United	1	2/12/2011	vs	Man City	W 2-1	2	11	5		479	49.7	16	2	0	2
18	Man United	1	4/17/2010	@	Man City	W 1-0	1	15	3		441	56.3	12	1	0	3
19	Man United	1	9/20/2009	vs	Man City	W 4-3	4	24	8		480	61.0	15	2	0	3
20	Man United	1	11/30/2008	@	Man City	W 1-0	1	14	6		447	54.4	16	6	1	2
21	Man United	1	5/5/2007	@	Man City	W 1-0	1	8	2		515	59.7	11	2	0	2
22	Man United	1	11/18/2000	@	Man City	W 1-0	1							1	0	1
23	Man United	1	4/6/1996	@	Man City	W 3-2	3							3	0	2
24	Man United	1	10/14/1995	vs	Man City	W 1-0	1							1	0	2
25	Man United	1	11/7/1993	@	Man City	W 3-2	3							1	0	1