Kevin De Bruyne has 23 goals and 19 assists in 76 appearances in the Premier League against Big Six opponents in his career.
| NAME | DATE | CLUB | OPP | MIN | G | A | XG | XA | PK | FK | SH | SOT | WOOD | TCH | TCH-BOX | OFF | FOUL | YC | RC | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | K. De Bruyne | 8/26/2013 |  Chelsea | @ |  Man United | 60 | 0 | 0 | 0 | 1 | 0 | ||||||||||
| 2 |  | K. De Bruyne | 9/26/2015 |  Man City | @ |  Tottenham | 90 | 1 | 0 | 0 | 0 | 3 | 2 | 0 | 68 | 0 | 0 | 0 | 0 | 0 | ||
| 3 | | K. De Bruyne | 10/25/2015 | Man City | @ | Man United | 90 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 48 | 0 | 0 | 1 | 0 | 0 | ||
| 4 | | K. De Bruyne | 11/21/2015 | Man City | vs |  Liverpool | 90 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 86 | 0 | 0 | 0 | 0 | 0 | ||
| 5 | | K. De Bruyne | 12/21/2015 | Man City | @ |  Arsenal | 90 | 0 | 0 | 0 | 0 | 3 | 1 | 0 | 93 | 0 | 0 | 2 | 0 | 0 | ||
| 6 | | K. De Bruyne | 4/16/2016 | Man City | @ | Chelsea | 90 | 0 | 0 | 0 | 0 | 3 | 2 | 0 | 67 | 0 | 0 | 2 | 0 | 0 | ||
| 7 | | K. De Bruyne | 5/8/2016 | Man City | vs | Arsenal | 90 | 1 | 0 | 0 | 0 | 3 | 2 | 0 | 65 | 0 | 1 | 0 | 0 | 0 | ||
| 8 | | K. De Bruyne | 9/10/2016 |  Man City | @ | Man United | 90 | 1 | 0 | 0 | 0 | 6 | 2 | 2 | 74 | 7 | 0 | 0 | 0 | 0 | ||
| 9 | | K. De Bruyne | 12/3/2016 | Man City | vs | Chelsea | 90 | 0 | 0 | 0 | 0 | 2 | 1 | 1 | 99 | 4 | 0 | 4 | 0 | 0 | ||
| 10 | | K. De Bruyne | 12/18/2016 | Man City | vs | Arsenal | 84 | 0 | 1 | 0 | 0 | 3 | 1 | 1 | 82 | 4 | 0 | 2 | 1 | 0 | ||
| 11 | | K. De Bruyne | 12/31/2016 | Man City | @ | Liverpool | 90 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 57 | 3 | 0 | 0 | 0 | 0 | ||
| 12 | | K. De Bruyne | 1/21/2017 | Man City | vs | Tottenham | 90 | 1 | 0 | 0 | 0 | 3 | 1 | 0 | 77 | 8 | 0 | 2 | 0 | 0 | ||
| 13 | | K. De Bruyne | 3/19/2017 | Man City | vs | Liverpool | 90 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 99 | 3 | 1 | 1 | 0 | 0 | ||
| 14 | | K. De Bruyne | 4/2/2017 | Man City | @ | Arsenal | 90 | 0 | 1 | 0 | 0 | 2 | 0 | 1 | 68 | 2 | 0 | 1 | 0 | 0 | ||
| 15 | | K. De Bruyne | 4/5/2017 | Man City | @ | Chelsea | 79 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 53 | 1 | 0 | 0 | 0 | 0 | ||
| 16 | | K. De Bruyne | 4/27/2017 | Man City | vs | Man United | 90 | 0 | 0 | 0 | 0 | 3 | 1 | 0 | 86 | 2 | 0 | 0 | 0 | 0 | ||
| 17 | | K. De Bruyne | 9/9/2017 | Man City | vs | Liverpool | 90 | 0 | 2 | 0 | 0 | 2 | 1 | 0 | 74 | 2 | 0 | 0 | 0 | 0 | ||
| 18 | | K. De Bruyne | 9/30/2017 | Man City | @ | Chelsea | 90 | 1 | 0 | 0 | 0 | 2 | 2 | 0 | 88 | 0 | 0 | 2 | 0 | 0 | ||
| 19 | | K. De Bruyne | 11/5/2017 | Man City | vs | Arsenal | 90 | 1 | 0 | 0 | 0 | 2 | 2 | 0 | 85 | 5 | 0 | 4 | 0 | 0 | ||
| 20 | | K. De Bruyne | 12/10/2017 | Man City | @ | Man United | 90 | 0 | 0 | 0 | 0 | 2 | 1 | 0 | 103 | 1 | 0 | 0 | 0 | 0 | ||
| 21 | | K. De Bruyne | 12/16/2017 | Man City | vs | Tottenham | 90 | 1 | 0 | 0 | 0 | 2 | 2 | 0 | 79 | 4 | 0 | 3 | 0 | 0 | ||
| 22 | | K. De Bruyne | 1/14/2018 | Man City | @ | Liverpool | 90 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 75 | 1 | 1 | 1 | 0 | 0 | ||
| 23 | | K. De Bruyne | 3/1/2018 | Man City | @ | Arsenal | 90 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 90 | 2 | 0 | 0 | 0 | 0 | ||
| 24 | | K. De Bruyne | 3/4/2018 | Man City | vs | Chelsea | 90 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 96 | 1 | 0 | 3 | 0 | 0 | ||
| 25 | | K. De Bruyne | 4/7/2018 | Man City | vs | Man United | 18 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 27 | 1 | 0 | 1 | 0 | 0 | ||
| Total | 5,806 | 23 | 19 | 2 | 7 | 0 | ||||||||||||||||
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| Team | W | D | L | GD | PTS | |
|---|---|---|---|---|---|---|
| 1 |  Barcelona | 19 | 3 | 5 | 48 | 60 |
| 2 |  Real Madrid | 18 | 6 | 4 | 32 | 60 |
| 3 |  Atlético Madrid | 16 | 8 | 4 | 24 | 56 |
| 4 |  Athletic Club | 14 | 10 | 4 | 22 | 52 |
| 5 |  Villarreal | 12 | 8 | 7 | 11 | 44 |
| 6 |  Real Betis | 12 | 8 | 8 | 3 | 44 |
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