Harry Kane had a hat trick, 12 goals and 6 assists in 16 appearances against Southampton in the Premier League in his career.

Harry Kane stats vs southampton in his career

	NAME	DATE	CLUB		OPP	MIN	G	A	XG	XA	PK	SH	SOT	WOOD	TCH	TCH-BOX	OFF	FOUL
1	Harry Kane H. Kane	10/5/2014	Tottenham	vs	Southampton	1	0	0			0	0	0	0	0	0	0	0
2	Harry Kane H. Kane	4/25/2015	Tottenham	@	Southampton	90	0	1			0	1	0	0	39	0	0	1
3	Harry Kane H. Kane	12/19/2015	Tottenham	@	Southampton	90	1	0	0.54	0.00	0	2	2	0	48	0	0	0
4	Harry Kane H. Kane	5/8/2016	Tottenham	vs	Southampton	90	0	0	0.61	0.02	0	6	1	0	34	0	1	0
5	Harry Kane H. Kane	12/28/2016	Tottenham	@	Southampton	89	1	0	0.88	0.00	0	3	1	0	22	5	0	1
6	Harry Kane H. Kane	12/26/2017	Tottenham	vs	Southampton	90	3	0	1.91	0.00	0	8	3	0	42	6	0	0
7	Harry Kane H. Kane	1/21/2018	Tottenham	@	Southampton	90	1	0	0.50	0.02	0	3	1	0	40	9	0	1
8	Harry Kane H. Kane	12/5/2018	Tottenham	vs	Southampton	90	1	1	0.50	0.49	0	3	2	0	25	4	1	1
9	Harry Kane H. Kane	3/9/2019	Tottenham	@	Southampton	90	1	0	0.65	0.08	0	8	2	1	45	10	1	0
10	Harry Kane H. Kane	9/28/2019	Tottenham	vs	Southampton	90	1	0	0.26	0.00	0	3	1	0	45	6	1	0
11	Harry Kane H. Kane	1/1/2020	Tottenham	@	Southampton	75	0	0	0.09	0.06	0	3	3	0	27	1	2	1
12	Harry Kane H. Kane	9/20/2020	Tottenham	@	Southampton	84	1	4	0.89	1.28	0	2	1	0	27	1	1	0
13	Harry Kane H. Kane	12/28/2021	Tottenham	@	Southampton	90	1	0	0.97	0.12	1	4	2	0	44	5	2	0
14	Harry Kane H. Kane	2/9/2022	Tottenham	vs	Southampton	90	0	0	0.15	0.54	0	2	1	0	43	2	1	0
15	Harry Kane H. Kane	8/6/2022	Tottenham	vs	Southampton	90	0	0	0.15	0.28	0	2	2	0	42	4	0	1
16	Harry Kane H. Kane	3/18/2023	Tottenham	@	Southampton	90	1	0	0.35	0.00	0	4	1	0	28	4	1	1
	Total					1,329	12	6			1	54	23	1	551	57	11	7