Lionel Messi has scored the most career goals by a South American in Europe's top five leagues, with 496 goals in LaLiga and Ligue 1.

	NAME	G	M	MIN	START	G/M	A	G+A	PK
1	Lionel Messi L. Messi	496	578	47,162	520	0.86	136	632	60
2	Edinson Cavani E. Cavani	267	479	35,355	394	0.56	41	308	40
3	Sergio Agüero S. Agüero	258	454	33,350	386	0.57	47	305	28
4	Luis Suárez L. Suárez	247	368	29,863	336	0.67	96	343	14
5	Gonzalo Higuaín G. Higuaín	237	428	30,147	338	0.55	29	266	15
6	Alfredo Di Stéfano A. Di Stéfano	227	329	29,610	329	0.69			17
7	José João Altafini J. João Altafini	217	458	39,038	429	0.47			15
8	Claudio Pizarro C. Pizarro	199	511	31,375	325	0.39	34	233	10
9	Gabriel Omar Batistuta G. Omar Batistuta	184	318	27,116	306	0.58			14
10	Ronaldo	175	252	19,912	232	0.69			23
11	Hernán Crespo H. Crespo	173	389	26,312	301	0.44	1	174	14
12	Anderson da Silva A. da Silva	167	306	23,120	259	0.55			13
13	Luis Vinicio L. Vinicio	155	348	31,185	348	0.45			15
14	Alexis Sánchez A. Sánchez	153	483	30,929	343	0.32	73	226	7
15	Neymar Jr N. Jr	150	235	19,406	218	0.64	83	233	31
16	Enrique Omar Sívori E. Omar Sívori	147	278	24,570	278	0.53			10
17	Mauro Icardi M. Icardi	144	283	20,558	228	0.51	32	176	20
18	Élber de Souza É. de Souza	144	290	22,051	257	0.50			0
19	Diego Forlán D. Forlán	140	321	22,766	255	0.44	9	149	14
20	Diego Milito D. Milito	139	267	20,618	237	0.52	11	150	31
21	Radamel Falcao R. Falcao	131	284	17,336	188	0.46	15	146	28
22	Paulo Dybala P. Dybala	129	349	23,842	277	0.37	66	195	33
23	Mario Alberto Kempes M. Alberto Kempes	126	222	18,895	218	0.57			26
24	Duván Zapata D. Zapata	124	326	22,007	253	0.38	43	167	7
25	Rubén Sosa R. Sosa	124	358	28,890	330	0.35			20